World cancer report 2014 / / edited by Bernard W. Stewart and Christopher P. Wild

• Record Nr.: UNINA9910463943703321
• Pubbl/distr/stampa: Lyon, France : , : International Agency for Research on Cancer, , 2014
• ISBN: 92-832-0432-8; 92-832-0443-3; 92-832-0434-4
• Descrizione fisica: 1 online resource (1900 p.)
• Disciplina: 362.196994
• Soggetti: Cancer - Epidemiology; Cancer - Etiology; Cancer - Prevention; World health; Electronic books.
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Front Cover; Title Page; Copyright Page; World Cancer Report 2014; Contributors; Contents; Perspectives; Foreword; Preface; Introduction; 1 Cancer worldwide; 1.1 The global and regional burden of cancer; 1.2 Transitions in human development and the global cancer burden; 1.3 Childhood cancer; Elizabeth H. Blackburn; Reconciling stress and cancer: insights from telomeres; Genetic susceptibility to tobacco-related cancers; 2.3 Alcohol consumption; Inflammation and cancer; Do infections play a role in breast cancer?; 2 Cancer etiology; Challenges of measuring diet in cancer epidemiological studies and new perspectivesSingle-nucleotide polymorphisms relevant to meat consumption and cancer risk; Diet and the gut microbiome; Evaluating carcinogens: dioxins and dioxin-like substances; Preventing occupational cancer: successes and failures; An IARC announcement that made waves; Bisphenol A and cancer; Pesticides and cancer; Breast implants and cancer; TP53 mutations and human cancer; Gene-environment interactions and breast cancer DNA repair polymorphisms and human cancer; Therapeutic implications of dysregulated DNA damage signallingThe non-coding RNA revolution in medical research; Causes and consequences of microRNA dysregulation in cancer; Stem cells in cancer: determinants of clinical outcome?; 3 Cancer biology; Role of the innate and acquired immune systems in mammary development and breast cancer; Premortem autophagy and endoplasmic reticulum stress as immunogenic signals in cancer therapy; 4 Cancer prevention; 4.1 Changing behaviours - tobacco control; Australia's plain packaging of tobacco products; Tobacco and China; 4.2 Changing behaviours - physical activity and weight controlEnergy restriction, age, and cancer risk; EPIC as a model study vehicle; 4.3 Designing and evaluating population-wide campaigns; 4.4 Prevention strategies common to noncommunicable diseases; The global economics of chronic and noncommunicable diseases; 4.5 Legislative and regulatory initiatives; Environmental pollution: old and new; Taxing sugar-sweetened beverages: the Brazilian case; 4.6 Vaccination; Early implementation and monitoring of HPV vaccination in Bhutan; Introduction and monitoring of a national HPV vaccination programme in Rwanda4.7 Screening - principles; 4.8 Screening - implementation; A guide to the epidemiology data in World Cancer Report; 5.1 Lung cancer; Earliest molecular evidence of tobacco-induced injury in the airway; Biomarkers of air pollution; 5.2 Breast cancer; Biological mechanisms mediating reduced breast cancer risk through physical activity; Treatment determined by BRCA1/2 mutation; 5.3 Oesophageal cancer; Risk of malignant progression in Barrett oesophagus patients; 5.4 Stomach cancer; Gastric cancer prevention; 5 Cancer by organ site
• Sommario/riassunto: This book from the International Agency for Research on Cancer the specialized cancer agency of the World Health Organization provides a unique global view of cancer including cancer patterns causes and prevention. The World Cancer Report series is recognized as an authoritative source of global perspective and information on cancer. The first volume appeared in 2003 and the second in 2008. This third volume in the series encompasses both established knowledge and recent research achievement. World Cancer Report provides a professional multidisciplinary assessment of all aspects of the geograp