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Record Nr. |
UNINA9910462913103321 |
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Autore |
Matson Robert S. |
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Titolo |
Applying genomic and proteomic microarray technology in drug discovery / / Robert S. Matson |
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Pubbl/distr/stampa |
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Boca Raton : , : Taylor & Francis, , 2013 |
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ISBN |
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0-429-10783-8 |
1-4398-5564-1 |
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Edizione |
[2nd ed.] |
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Descrizione fisica |
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1 online resource (313 p.) |
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Disciplina |
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Soggetti |
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High throughput screening (Drug development) |
DNA microarrays |
Protein microarrays |
Pharmacogenomics |
Proteomics |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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Omics & microarrays revisited -- The commercial microarray -- Supports & surface chemistries -- The arraying process -- Gene expression microarray-based applications -- Protein microarray applications -- Multiplex assays. |
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Sommario/riassunto |
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Microarrays play an increasingly significant role in drug discovery. The commercial landscape has changed dramatically over the past few years and researchers have made great advancements with regard to construction and use. Now in its second edition, Applying Genomic and Proteomic Microarray Technology in Drug Discovery highlights, describes, and evaluates current scientific research using microarray technology in genomic and proteomic applications.Updated and revised to reflect recent progress in the field, the second edition discusses: Expanded omics-driven applications, including the areas |
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2. |
Record Nr. |
UNISA996411326003316 |
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Autore |
List Mattis |
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Titolo |
Sequence Comparison in Historical Linguistics / / Mattis List |
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Pubbl/distr/stampa |
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De Gruyter, 2021 |
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Düsseldorf : , : düsseldorf university press, , [2014] |
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©2021 |
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ISBN |
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Descrizione fisica |
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1 online resource (308 p.) |
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Collana |
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Dissertations in Language and Cognition |
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Soggetti |
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LANGUAGE ARTS & DISCIPLINES / General |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di contenuto |
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Frontmatter -- Acknowledgements -- Contents -- List of Figures -- List of Tables -- 1 Introduction -- 2 Historical Linguistics -- 3 Sequence Comparison -- 4 Sequence Comparison in Historical Linguistics -- 5 Conclusion -- Bibliography -- Sources -- Dictionaries and Databases -- Supplementary Material -- List of Abbreviations -- Indices -- Appendix A. Language-Specific Resources -- Appendix B. Sequence Modelling -- Appendix C. Phonetic Alignment -- Appendix D. Cognate Detection |
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Sommario/riassunto |
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The comparison of sound sequences (words, morphemes) constitutes the core of many techniques and methods in historical linguistics. With the help of these techniques, corresponding sounds can be determined, historically related words can be identified, and the history of languages can be uncovered. So far, the application of traditional techniques for sequence comparison is very tedious and time-consuming, since scholars have to apply them manually, without computational support. In this study, algorithms from bioinformatics are used to develop computational methods for sequence comparison in historical linguistics. The new methods automatize several steps of the traditional comparative method and can thus help to ease the painstaking work of language comparison. Dissertations in Language and Cognition This series explores issues of mental representation, linguistic structure and representation, and their interplay. The |
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research presented in this series is grounded in the idea explored in the Collaborative Research Center 'The structure of representations in language, cognition and science' (SFB 991) that there is a universal format for the representation of linguistic and cognitive concepts. |
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