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Record Nr. |
UNINA9910462903903321 |
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Titolo |
Connexin cell communication channels : roles in the immune system and immunopathology / / edited by Ernesto Oviedo-Orta, Brenda R. Kwak, William Howard Evans |
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Pubbl/distr/stampa |
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Boca Raton : , : Taylor & Francis/CRC Press, , 2013 |
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ISBN |
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0-429-16585-4 |
1-4398-6258-3 |
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Descrizione fisica |
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1 online resource (363 p.) |
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Altri autori (Persone) |
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Oviedo-OrtaErnesto |
KwakBrenda R |
EvansW. Howard |
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Disciplina |
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Soggetti |
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Gap junctions (Cell biology) |
Connexins |
Inflammation |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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Front Cover; Contents; Preface; Editors; Contributors; Prequel: Gap Junctions, Hemichannels, and Cell-to-Cell Signalling; Chapter 1 - Communication in the Immune System by Connexin Channels; Chapter 2 - Gap Junctions and Connexins in the Hematopoietic-Immune System: Structural Considerations; Chapter 3 - Approaches for Studying the Role(s) of Gap Junctions in the Immune System; Chapter 4 - Gap Junctions in Antigen-Presenting Cells; Chapter 5 - Connect the Immune System: Roles of Gap Junctions in Antigen Presentation and T Cell Activation |
Chapter 6 - Gap Junctions and Connexins in the Immune Defense Against TumorsChapter 7 - Connexins in Atherosclerosis; Chapter 8 - Connexins in Lung Function and Inflammation; Chapter 9 - Effect of Oxidative Stress on Connexins in the Vasculature; Chapter 10 - Regulation of Gap Junctions and Cellular Coupling within the Microvasculature in Response to Acute Inflammation; Chapter 11 - Impact of Microglial Activation on Astroglial Connexin Expression and |
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Function in Brain Inflammation; Chapter 12 - A Role for Connexins in Inflammatory Disorders of the Epidermis |
Chapter 13 - Translating Basic Research on Cx43 Gap Junctions into Therapies for Reducing Scarring and Cardiac ArrhythmiaChapter 14 - Connexin-Based Therapeutic Approaches to Inflammation in the Central Nervous System; Chapter 15 - Enhancing Epithelial Tissue Repair and Reducing Inflammation by Targeting Connexins; Back Cover |
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Sommario/riassunto |
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Plasma membrane-associated channels known as gap junctions, along with their protein building blocks-connexins-have an important functional role in a range of immunological processes, including heart function, cell growth and specialization, and early development. Spanning basic science and potential clinical applications, Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology assembles and synthesizes four decades of the most important research carried out in this field. The book first provides a historical overview of the discovery of these membrane channels in |
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