1.

Record Nr.

UNINA9910462080103321

Titolo

Evolution of translational omics [[electronic resource] ] : lessons learned and the path forward / / Committee on the Review of Omics-Based Tests for Predicting Patient Outcomes in Clinical Trials; Board on Health Care Services; Board on Health Sciences Policy ; Christine M. Micheel, Sharyl J. Nass, and Gilbert S. Omenn, editors ; Institutes of Medicine of the National Academies

Pubbl/distr/stampa

Washington, D.C., : National Academies Press, c2012

ISBN

1-283-63640-9

0-309-22419-5

Descrizione fisica

1 online resource (338 p.)

Altri autori (Persone)

MicheelChristine

NassSharyl J

OmennGilbert S

Disciplina

572.33

Soggetti

Genomics - Technology

Genomics - Data processing

Genetic translation - Technology

Biomolecules - Analysis

Biomolecules - Data processing

Bioinformatics - Technology

Biotechnology

Data mining - Analysis

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references.

Nota di contenuto

""Front Matter""; ""Reviewers""; ""Acknowledgments""; ""Contents""; ""Boxes, Figures, and Tables""; ""Summary""; ""1 Introduction""; ""2 Omics-Based Clinical Discovery: Science, Technology, and Applications""; ""3 Best Practices for Omics-Based Test Validation Prior to Use for Patient Management Decisions in a Clinical Trial Setting""; ""4 Evaluation of Omics-Based Tests for Clinical Utility and Use""; ""5 Responsible Parties""; ""6 Lessons from the Case Studies""; ""Appendix



A: Case Studies""

""Appendix B: Gene Expression Based Tests Developed at Duke University and Used in Clinical Trials""""Appendix C: Introduction to Biomarkers""; ""Appendix D: Reporting Guidelines""; ""Appendix E: Committee Member and Staff Biographies""; ""Appendix F: Information Gathering Sessionsand Speakers""; ""Acronyms and Abbreviations""; ""Glossary""