1.

Record Nr.

UNINA9910461462103321

Autore

Zivin Justin A

Titolo

tPA for stroke [[electronic resource] ] : the story of a controversial drug / / Justin A. Zivin, John Galbraith Simmons

Pubbl/distr/stampa

New York, : Oxford University Press, 2011

ISBN

1-283-12126-3

9786613121264

0-19-978094-3

Descrizione fisica

1 online resource (206 p.)

Altri autori (Persone)

SimmonsJohn <1949->

Disciplina

616.8/106

Soggetti

Cerebrovascular disease - Chemotherapy - History

Tissue plasminogen activator - Therapeutic use - History

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Code stroke on Market street -- Clot-buster : the natural history -- Dead or alive -- Brain-O -- The brain doctors cometh : slowly -- What emergency? -- Money and brains -- Deer in the headlights -- Call 911, 112, 15 ... even 999 -- Persistence of a most controversial drug -- Through the looking glass -- Post-script.

Sommario/riassunto

Without warning stroke can paralyze, blind, or kill. Some victims recover, but many do not and may even suffer another disabling or fatal attack. The drug known as tPA can drastically reduce the long-term disability associated with stroke, but despite its near-miraculous capabilities and the growing support of most neurologists, it has been slow to win acceptance as the standard of care in emergency departments nationwide. tPA for Stroke chronicles how this remarkable drug came to be tested in stroke victims, its early years in development by the pharmaceutical giant Genentech, and its eventua