Basic pharmacokinetics / / Mohsen A. Hedaya

• Record Nr.: UNINA9910460567003321
• Autore: Hedaya Mohsen A.
• Pubbl/distr/stampa: Boca Raton : , : CRC Press, , 2012
• ISBN: 0-429-25125-4; 1-4398-5075-5
• Edizione: [Second edition.]
• Descrizione fisica: 1 online resource (581 p.)
• Collana: CRC Press Pharmacy Education Series
• Disciplina: 615/.7
• Soggetti: Pharmacokinetics; Electronic books.
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references at the end of each chapters.
• Nota di contenuto: Front Cover; Contents; Preface; Author; Chapter 1: Introduction to Pharmacokinetics; Chapter 2: Review of Mathematical Fundamentals; Chapter 3: Drug Pharmacokinetics Following a Single IV Bolus Administration: Drug Distribution; Chapter 4: Drug Pharmacokinetics Following a Single IV Bolus Administration: Drug Clearance; Chapter 5: Drug Pharmacokinetics Following a Single IV Bolus Administration: The Rate of Drug Elimination; Chapter 6: Drug Absorption Following Extravascular Administration: Biological, Physiological, and Pathological Considerations; Chapter 7: Drug Absorption Following Extravascular Administration: Molecular and Physicochemical ConsiderationsChapter 8: Drug Absorption Following Extravascular Administration: Formulation Factors; Chapter 9: Drug Pharmacokinetics Following Single Oral Drug Administration: The Rate of Drug Absorption; Chapter 10: Drug Pharmacokinetics Following Single Oral Drug Administration: The Extent of Drug Absorption; Chapter 11: Bioequivalence; Chapter 12: Drug Pharmacokinetics during Constant Rate IV Infusion: The Steady-State Principle; Chapter 13: Steady State during Multiple Drug Administration; Chapter 14: Renal Drug ExcretionChapter 15: Metabolite Pharmacokinetics; Chapter 16: Nonlinear Pharmacokinetics; Chapter 17: Multicompartment Pharmacokinetic Models; Chapter 18: Drug Pharmacokinetics Following Administration by Intermittent Intravenous ; Infusion; Chapter 19: Pharmacokinetic-Pharmacodynamic Modeling; Chapter 20: Noncompartmental Approach in Pharmacokinetic Data Analysis; Chapter 21: Physiological Approach to Hepatic Clearance; Chapter 22: Physiologically Based Pharmacokinetic Models; Chapter 23: Therapeutic Drug Monitoring; Chapter 24: Pharmacokinetics in Special Patient PopulationsChapter 25: Pharmacokinetic Drug-Drug Interactions; Chapter 26: Pharmacogenetics: The Genetic Basis of Pharmacokinetic and Pharmacodynamic Variability; Chapter 27: Applications of Computers in Pharmacokinetics; Chapter 28: The Companion CD; Solutions for the Practice Problems; Back Cover
• Sommario/riassunto: Introduction to PharmacokineticsReview of Mathematical Fundamentals Drug Pharmacokinetics Following a Single IV Bolus Administration: Drug DistributionDrug Pharmacokinetics Following a Single IV Bolus Administration: Drug ClearanceDrug Pharmacokinetics Following a Single IV Bolus Administration: The Rate of Drug EliminationDrug Absorption Following Extravascular Administration: Biological, Physiological, and Pathological Considerations Drug Absorption Following Extravascular Administration: Molecular and Physicochemical ConsiderationsDrug Absorption Following Extravascular Administration: Form