1.

Record Nr.

UNINA9910460442103321

Autore

Wan Shibiao

Titolo

Machine learning for protein subcellular localization prediction / / Shibiao Wan, Man-Wai Mak

Pubbl/distr/stampa

Berlin, Germany ; ; Boston, Massachusetts : , : De Gruyter, , 2015

©2015

ISBN

1-5015-0150-X

1-5015-0152-6

Descrizione fisica

1 online resource (210 p.)

Classificazione

WC 7700

Disciplina

572/.696

Soggetti

Proteins - Physiological transport - Data processing

Machine learning

Probabilities - Data processing

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Front matter -- Preface -- Contents -- List of Abbreviations -- 1. Introduction -- 2. Overview of subcellular localization prediction -- 3. Legitimacy of using gene ontology information -- 4. Single-location protein subcellular localization -- 5. From single- to multi-location -- 6. Mining deeper on GO for protein subcellular localization -- 7. Ensemble random projection for large-scale predictions -- 8. Experimental setup -- 9. Results and analysis -- 10. Properties of the proposed predictors -- 11. Conclusions and future directions -- A. Webservers for protein subcellular localization -- B. Support vector machines -- C. Proof of no bias in LOOCV -- D. Derivatives for penalized logistic regression -- Bibliography -- Index

Sommario/riassunto

Comprehensively covers protein subcellular localization from single-label prediction to multi-label prediction, and includes prediction strategies for virus, plant, and eukaryote species. Three machine learning tools are introduced to improve classification refinement, feature extraction, and dimensionality reduction.