1.

Record Nr.

UNINA9910457433203321

Titolo

Substrata versus universals in Creole genesis [[electronic resource] ] : papers from the Amsterdam Creole Workshop, April 1985 / / edited by Pieter Muysken & Norval Smith

Pubbl/distr/stampa

Amsterdam ; ; Philadelphia, : J. Benjamins, 1986

ISBN

1-283-32857-7

9786613328571

90-272-7941-1

Descrizione fisica

1 online resource (323 p.)

Collana

Creole language library ; ; v. 1

Altri autori (Persone)

MuyskenPieter

SmithNorval

Disciplina

417/.2

Soggetti

Creole dialects

Substratum (Linguistics)

Linguistic universals

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographies.

Nota di contenuto

SUBSTRATA VERSUS UNIVERSALS IN CREOLE GENESIS; Editorial page; Title page; Copyright page; Preface; Table of contents; Introduction: Problems in the Identification of Substratum Features in the Creole Languages; Who, What, Where and Why?; The contributions to this volume; Synthesis; REFERENCES; The Language Bioprogram Hypothesis: Déjà Vu?; REFERENCES; Creoles and West African Languages: a Case of Mistaken Identity?; NOTES; REFERENCES; Bonnet Blanc et Blanc Bonnet: Adjective-Noun Order, Substratum and Language Universals; 1. The problem and some data; 2. Adjective order in Tok Pisin

3. Substratum vs. other explanations4. Conclusions; NOTES; REFERENCES; Semantic Transparency as a Factor in Creole Genesis; NOTE; REFERENCES; The Domestic Hypothesis, Diffusion and Componentiality. An Account of Atlantic Anglophone Creole Origins; 1. Evidence of a pre-1800 anglophone creole on the Coast; 2. Evidence of long-term British settlement on the Coast; 3. Evidence of domestic unions between Europeans and Africans; 4. Emergence of Creole



societies; 5. Role of the grumettoes; 6. Evidence for the age and provenance of Guinea Coast Creole English

(1) The nature of the English first heard by Africans(2) The linguistic situation in Guinea encountered by the English speakers; (3) The emergence of creolized English from English and African contact; (4) Its further modification by second-language speakers; (5) Its transmission overseas and the development of the Western creoles; 7. Summary; WORKS CONSULTED; Genesisand Development of the Equative Copula in Sranan; 1. The data; 2. The pronominal origin of copular da; 3. The historical development of the equative copula

4. Substrata and universals in the differentiation of the equative category5. Summary and conclusion; NOTES; APPENDIX: Historical sources used for this study; REFERENCES; The Universalistand Substrate Hypotheses Complement One Another; 1. Why Are We Discussing Only the Universalist and Substrate Hypotheses?; 2. Some High Marks for the Universalist Hypothesis; 3. Is the Substrate Hypothesis All Wrong?; 4. Double Standards regarding Atlantic and Oceanic Pidgins and Creoles?; 5. Couple of Relevant Miscellanea; NOTES; REFERENCES; Universals, Substrata and the Indian Ocean Creoles

1. Demography and the evolution of Reu and IdF2. Agglutination; 3. The predicate marker system in IdF and other Creoles; 4. An example of Indo-Aryan syntactic influence in Mauritian Creole; 5. Concluding remarks; NOTES; ANNEXE 1; BIBLIOGRAPHY; DoubleNegationand the Genesis of Afrikaans; 1. Preliminary considerations; 2. Afrikaans and other languages once spoken at the Cape; 2.1. Introductory remarks; 2.2. Various views on the development of Afrikaans (Hesseling e.a.); 2.3. The linguistic situation at the Cape from a historical point of view; 2.4. Consequences for research

3. Double negation in Afrikaans

Sommario/riassunto

Two of the most prominent hypotheses about why the structures of the Creole languages of the Atlantic and the Pacific differ are the universalist and he substrate hypotheses. The universalist hypothesis claims, essentially, that the particular grammatical properties of Creole languages directly reflect universal aspects of the human language capacity, and thus Creole genesis involves, then, the stripping away of the accretions of language history. The substrate hypothesis claims, on the other hand, that creole genesis results from the confrontation of two systems, the native languages of the c



2.

Record Nr.

UNINA9910460059903321

Autore

Cristini Vittorio <1970->

Titolo

Multiscale modeling of cancer : an integrated experimental and mathematical modeling approach / / Vittorio Cristini, John Lowengrub [[electronic resource]]

Pubbl/distr/stampa

Cambridge : , : Cambridge University Press, , 2010

ISBN

1-107-21140-9

1-282-77073-X

9786612770739

0-511-90148-8

0-511-79912-8

0-511-90227-1

0-511-79772-9

0-511-78145-8

0-511-90069-4

Descrizione fisica

1 online resource (xix, 278 pages) : digital, PDF file(s)

Disciplina

362.196/994

Soggetti

Cancer - Research - Mathematical models

Multiscale modeling

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Title from publisher's bibliographic system (viewed on 05 Oct 2015).

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Part I. Theory: 1. Introduction; 2. Biological background; 3. Continuum tumor modeling: single phase; 4. Analysis and calibration of single-phase continuum tumor models; 5. Continuum tumor modeling: multiphase; 6. Discrete cell modeling; 7. Hybrid continuum -- discrete models; 8. Numerical schemes -- Part II. Applications: 9. Continuum tumor modeling: a multidisciplinary approach; 10. Agent-based cell modeling: application to breast cancer.

Sommario/riassunto

Mathematical modeling, analysis and simulation are set to play crucial roles in explaining tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial scales. This book, the first to integrate state-of-the-art numerical techniques with experimental data, provides an in-depth assessment of tumor cell modeling at



multiple scales. The first part of the text presents a detailed biological background with an examination of single-phase and multi-phase continuum tumor modeling, discrete cell modeling, and hybrid continuum-discrete modeling. In the final two chapters, the authors guide the reader through problem-based illustrations and case studies of brain and breast cancer, to demonstrate the future potential of modeling in cancer research. This book has wide interdisciplinary appeal and is a valuable resource for mathematical biologists, biomedical engineers and clinical cancer research communities wishing to understand this emerging field.

3.

Record Nr.

UNINA9910149597203321

Titolo

Albumin in Medicine : Pathological and Clinical Applications / / edited by Masaki Otagiri, Victor Tuan Giam Chuang

Pubbl/distr/stampa

Singapore : , : Springer Singapore : , : Imprint : Springer, , 2016

Edizione

[1st ed. 2016.]

Descrizione fisica

1 online resource (X, 277 p. 50 illus., 37 illus. in color.)

Disciplina

615

Soggetti

Pharmacology

Pharmaceutical chemistry

Pharmacology/Toxicology

Medicinal Chemistry

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references and index.

Sommario/riassunto

This book presents a comprehensive overview of medical and pharmaceutical applications of human serum albumin (HSA), with updates on structural aspects of albumin from the perspectives of X-ray crystallography and NMR, endogenous and exogenous ligand binding of albumin in various pathological conditions, and genetic variants and their phenotypes. Rapid progress and development of its applications have resulted in outstanding results for which albumin has



clearly been proven to be a robust biomaterial. Contributions from leading international experts in this field show how HSA is applied to diagnosis, therapy, drugs, and treatment, with a comprehensive introduction of HSA. This volume will appeal to scientists in pharmaceutical and medical research including pharmaceutical chemists, pharmacokineticists, toxicologists, and biochemists not only in academia but also in industry. Readers can effectively acquire the most recent knowledge of applications of HSA and its impact on human health in a single volume.