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Record Nr. |
UNINA9910459886503321 |
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Titolo |
Hormones and transport systems / / edited by Gerald Litwack ; contributors, Yasaman Aghazadeh [and thirty-eight others] |
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Pubbl/distr/stampa |
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Amsterdam, [Netherlands] : , : Academic Press, , 2015 |
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©2015 |
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ISBN |
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0-12-803008-9 |
0-12-803028-3 |
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Edizione |
[First edition.] |
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Descrizione fisica |
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1 online resource (584 p.) |
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Collana |
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Vitamins and Hormones, , 0083-6729 ; ; Volume ninety eight |
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Disciplina |
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Soggetti |
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Hormones |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references at the end of each chapters and index. |
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Nota di contenuto |
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Front Cover; Hormones and Transport Systems; Copyright; Former Editors; Contents; Contributors; Preface; Chapter One: Dietary I- Absorption: Expression and Regulation of the Na+/I- Symporter in the Intestine; 1. The Importance of Iodide in Human Health; 2. The Na+/I- Symporter; 2.1. Molecular identification of NIS; 2.2. NIS-mediated transport: Substrates and stoichiometry; 2.3. The role of physiological Na+ concentrations in NIS affinity for I-; 3. NIS Expression Beyond the Thyroid; 4. Targeting of NIS to the Plasma Membrane; 5. Hormonal Regulation of NIS Expression; 6. Dietary I- Absorption |
7. Regulation of Intestinal NIS Expression8. Conclusions and Future Directions; Acknowledgments; References; Chapter Two: Apical Iodide Efflux in Thyroid; 1. Introduction; 2. Iodide and Thyroid Hormone Synthesis; 2.1. Thyroid organization; 2.2. Thyroid hormone synthesis; 3. Vectorial Transport Processes in Epithelia and Thyroid I- Accumulation; 3.1. Brief overview of basic epithelial transport processes; 3.2. Basolateral iodide uptake; 3.3. Apical iodide release; 4. Chloride Transport Proteins and Luminal I- Translocation; 4.1. SLC26A4 (Pendrin); 4.1.1. SLC26A4, HCO3-, luminal pH |
4.2. Cystic fibrosis transmembrane conductance regulator4.2.1. CFTR and SLC26A4 interplay; 4.3. SLC5A8, a sodium-monocarboxylate |
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