1.

Record Nr.

UNINA9910459535203321

Titolo

ePro [[electronic resource] ] : electronic solutions for patient-reported data / / edited by Bill Byrom and Brian Tiplady

Pubbl/distr/stampa

Farnham, Surrey, England ; ; Burlington, VT, : Gower, c2010

ISBN

1-317-14191-1

1-317-14190-3

1-282-85767-3

9786612857676

1-4094-1242-3

Descrizione fisica

1 online resource (297 p.)

Altri autori (Persone)

ByromBill

TipladyBrian

Disciplina

610.285

Soggetti

Clinical trials - Data processing

Outcome assessment (Medical care) - Data processing

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Cover; Contents; List of Figures; List of Tables; Foreword; About the Editors; List of Contributors; Introduction; 1 Recall Bias: Understanding and Reducing Bias in PRO Data Collection; 2 Cognitive Interviewing: The use of Cognitive Interviews to Evaluate ePRO Instruments; 3 Data Quality and Power in Clinical Trials: A Comparison of ePRO and Paper in a Randomized Trial; 4 Regulation and Compliance; 5 Selection of a Suitable ePRO Solution: Benefit, Cost and Risk; 6 Patient Compliance in an ePRO Environment; 7 Computerized Clinical Assessments

8 Diary Design Considerations: Interface Issues and Patient Acceptability9 Equivalence Testing: Validation and Supporting Evidence When Using Modified PRO Instruments; 10 ePRO Applications and Personal Mobile Phone Use: Compliance Documentation and Patient Support; 11 Future Developments and Applications: Emerging Technologies and New Approaches to Patients; Index

Sommario/riassunto

Recently, there has been much open debate with the regulators around the use of ePRO in clinical drug submissions. US and European agencies



have approved new drugs that have included ePRO data in the submission dossier, but there are many questions around the adoption of the technology that concern the community. Bill Byrom and Brian Tiplady's ePro addresses these questions, reviews the new FDA guidance, and provides a very contemporary view on this important subject.