1.

Record Nr.

UNINA9910459062703321

Titolo

Handbook of chemoinformatics algorithms / / editors, Jean-Loup Faulon, Andreas Bender

Pubbl/distr/stampa

Boca Raton : , : Chapman & Hall/CRC, , 2010

ISBN

0-429-14091-6

1-4200-8299-X

Descrizione fisica

1 online resource (454 p.)

Collana

Chapman & Hall/CRC mathematical and computational biology series

Altri autori (Persone)

FaulonJean-Loup

BenderAndreas <1976->

Disciplina

542/.85

Soggetti

Cheminformatics

Algorithms

Graph theory

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Front Cover; Contents; Preface; Acknowledgments; Contributors; Chapter 1: Representing Two-Dimensional (2D) Chemical Structureswith Molecular Graphs; Chapter 2: Algorithms to Store and Retrieve Two-Dimensional (2D) Chemical Structures; 3 Three-Dimensional (3D) MolecularRepresentations; Chapter 4: Molecular Descriptors; 5 Ligand- andStructure-Based VirtualScreening; Chapter 6: Predictive Quantitative Structure-Activity Relationships Modeling; Chapter 7: Predictive Quantitative Structure-Activity Relationships Modeling; Chapter 8: Structure Enumeration and Sampling

Chapter 9: Computer-Aided Molecular DesignChapter 10: Computer-Aided Molecular Design; Chapter 11: Reaction Network Generation; Chapter 12: Open Source Chemoinformatics Software and DatabaseTechnologies; Chapter 13: Sequence Alignment Algorithms; Chapter 14: Machine Learning-Based Bioinformatics Algorithms; Chapter 15: Using Systems Biology Techniques to Determine Metabolic Fluxes and Metabolite Pool Sizes; Index; Back Cover

Sommario/riassunto

Describing the characteristics and limitations of key algorithms, this book covers various aspects of chemoinformatics, including structure



representation, molecular descriptors, similarity search, virtual screening, and structure-property model generation and validation.