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Record Nr. |
UNINA9910458671503321 |
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Autore |
Mushegian Arcady R |
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Titolo |
Foundations of comparative genomics [[electronic resource] /] / Arcady R. Mushegian |
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Pubbl/distr/stampa |
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Amsterdam ; ; Boston, : Academic Press, c2007 |
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ISBN |
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1-281-03696-X |
9786611036966 |
0-08-054609-9 |
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Descrizione fisica |
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1 online resource (276 p.) |
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Disciplina |
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Soggetti |
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Genomics |
Gene mapping |
Physiology, Comparative |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references (p. 238-257) and index. |
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Nota di contenuto |
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The beginning of computational genomics -- Finding sequence similarities -- Homology: can we get it right? -- Getting ready for the era of comparative genomics: the importance of viruses -- The first fact of comparative genomics: protein sequences are remarkably resilient in evolution -- The second fact of comparative genomics: functional convergence at the molecular level -- Prediction of function and reconstruction of metabolism from genomic data: homology-based approaches -- Prediction of function and reconstruction of metabolism: post-homology approaches -- Structural genomics: what does it tell us about life? -- How many protein families are there? -- Phylogenetic inference and the era of complete genomes -- Two stories about evolution -- Minimal and ancestral genomes -- Comparative genomics and systems biology. |
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Sommario/riassunto |
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This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, |
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