1.

Record Nr.

UNINA9910457731603321

Titolo

The sperm cell : production, maturation, fertilization, regeneration / / edited by Christopher J. De Jonge and Christopher L.R. Barratt [[electronic resource]]

Pubbl/distr/stampa

Cambridge : , : Cambridge University Press, , 2006

ISBN

1-107-15494-4

1-280-48006-8

9786610480067

0-511-22034-0

0-511-22123-1

0-511-21926-1

0-511-54511-8

0-511-31461-2

0-511-21994-6

Descrizione fisica

1 online resource (xi, 359 pages) : digital, PDF file(s)

Disciplina

612.61

Soggetti

Spermatozoa

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Title from publisher's bibliographic system (viewed on 05 Oct 2015).

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Cover; Half-title; Title; Copyright; Contents; Preface; List of contributors; 1 Mammalian spermatogenesis and sperm structure: anatomical and compartmental analysis; 2 Sperm chromatin stability and susceptibility to damage in relation to its structure; 3 Genomic and proteomic approaches to defining sperm production and function; 4 Sperm maturation in the human epididymis; 5 Controls of sperm motility; 5 6egulation of capacitation; 7 Reactive oxygen species: friend or foe; 8 Testing sperm manufacturing quality: the sperm-zona binding assay; 9 Genetics: a basic science perspective

10 Sex chromosome abnormalities and male infertility: a clinical perspective11 Epigenetic patterning in male germ cells: importance of DNA methylation to progeny outcome; 12 The DAZ gene family and human germ cell development from embryonic stem cells; Index



Sommario/riassunto

Originally published in 2006, this is a comprehensive and definitive account of the human male gamete. The volume summarizes many unique and revealing characteristics of the sperm cell. It provides a detailed overview of human sperm production, maturation and function, and looks at how these processes affect and influence fertility, infertility and ART. The volume thus provides a detailed review of the most important research and developments, augmented with pertinent references. This book will appeal to all practitioners and scientists in reproductive medicine and in particular to clinical scientists, graduate and post-graduate scientists, and laboratory personnel.