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Record Nr. |
UNINA9910457252903321 |
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Titolo |
Advances in antiviral drug design . Volume 5 [[electronic resource] /] / editor, E. De Clercq |
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Pubbl/distr/stampa |
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Greenwich, CT ; ; London, England, : Jai Press, 2007 |
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ISBN |
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1-281-11983-0 |
9786611119836 |
0-08-054824-5 |
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Descrizione fisica |
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1 online resource (265 p.) |
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Collana |
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Advances in antiviral drug design ; ; 5 |
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Altri autori (Persone) |
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Disciplina |
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616.9 |
616.9/25061/05 |
616.91061 |
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Soggetti |
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Antiviral agents |
Anti-infective agents |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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I. IntroductionII. Design; III. Synthesis; IV. Antiviral activity; Acknowledgements; References; Chapter 4. Synthesis and antiviral evaluation of broad spectrum, orally active analogs of cidofovir and other acyclic nucleoside phosphonates; I. Introduction; II. Synthesis of hexadecyloxypropyl and related esters of cidofovir; III. Antiviral evaluation and spectrum of activity; IV. Structure activity relationships; V. Cellular metabolism; VI. Oral pharmacokinetics and tissue distribution; VII. Antiviral activity in animal models of viral diseases |
VIII. Alkoxyalkyl esters of (S)-HPMPA and other acyclic nucleoside phosphonatesIX. Conclusions; Acknowledgements; References; Chapter 5. CCR5 antagonistsCCR5 antagonists for the treatment ofHIV infection and AIDS; I. Introduction; II. Inhibition of HIV entry; III. CCR5 as a drug target; IV. The discovery of novel CCR5 antagonists; V. Molecular mechanisms; VI. Resistance to CCR5 antagonists in vitro and in the clinic; VII. Conclusions; References; Chapter 6. The medicinal chemistry of the DATADATA and DAPYDAPY series of HIV-1HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIsNNRTIs) |
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AbstractI. Introduction; II. The diaryltriazine (DATA) series; III. The diarylpyrimidine (DAPY) series; IV. Conclusion; Acknowledgements; References; Index |
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Sommario/riassunto |
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Regularly reviewing the ""state-of-the-art"" developments in the antiviral drug research field, this latest volume spans the conceptual design and chemical synthesis of new antiviral compounds. It discusses their structure-activity relationship, mechanism and targets of action, pharmacological behavior, antiviral activity spectrum, and therapeutic potential for clinical use. |
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2. |
Record Nr. |
UNINA9910827975403321 |
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Autore |
Marples David R. |
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Titolo |
"Our glorious past" : Lukashenka's Belarus and the Great Patriotic War / / David R. Marples |
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Pubbl/distr/stampa |
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Stuttgart, Germany : , : Ibidem-Verlag, , [2014] |
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©2014 |
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ISBN |
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Descrizione fisica |
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1 online resource (437 p.) |
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Collana |
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Soviet and post-Soviet politics and society ; ; 124 |
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Disciplina |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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PREFACE; TABLE OF CONTENTS; ACKNOWLEDGEMENTS; NOTE ON TRANSLITERATION OF NAMES; INTRODUCTION: LUKASHENKA'S BELARUS; CHAPTER ONE: THE START OF THE WAR; Introduction; School Textbooks; Interlude: Soviet Rule Extends to Western Belarus; The Start of the Great Patriotic War; Evacuations; The View from the Military; CHAPTER TWO: THE GERMAN OCCUPATION REGIME; Introduction; School Textbooks; Life Under Occupation; Camps; Collaboration; The Holocaust; CHAPTER THREE: THE PARTISANS; Introduction; School Textbooks; Vasily Korzh; Sydir Kovpak; Organizing Partisans; The NKVD and NKGB; Operations |
Liniya Stalina (The Stalin Line)Monuments; a) Minsk; b) Other Areas of Belarus; c) Monuments Outside Belarus; Finding the Dead; CHAPTER |
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SEVEN: PUBLICIZING THE WAR; Museums; Conferences; Concerts and Public Displays; Commemorations; Books and Documentaries; The Fortress of War Movie; The 65th Anniversary of Liberation of Belarus, 2009; The 65th Anniversary of the Victory, 2010; CHAPTER EIGHT: HISTORICAL REVISIONISM; Background; Victory Day; War Losses; The Vilnius Declaration; Political Officers and Penal Battalions; Treatment of Veterans; Illia Kopyl and the Partisans; CONCLUSION |
BIBLIOGRAPHYINDEX |
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