1.

Record Nr.

UNINA9910456868603321

Titolo

Rare diseases and orphan products [[electronic resource] ] : accelerating research and development / / Committee on Accelerating Rare Diseases Research and Orphan Product Development, Board on Health Sciences Policy ; Marilyn J. Field and Thomas F. Boat, editors ; Institute of Medicine of the National Academies

Pubbl/distr/stampa

Washington, D.C., : National Academies Press, c2010

ISBN

1-283-04456-0

9786613044563

0-309-15807-9

Descrizione fisica

1 online resource (443 p.)

Altri autori (Persone)

FieldMarilyn J (Marilyn Jane)

BoatThomas F

Disciplina

615.19

Soggetti

Orphan drugs

Drugs - Design

Rare diseases - Treatment

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references (p. 249-282) and index.

Nota di contenuto

""Front Matter""; ""Acknowledgments""; ""Reviewers""; ""Preface""; ""Contents""; ""Boxes, Figures, and Tables""; ""Summary""; ""1 Introduction""; ""2 Profile of Rare Diseases""; ""3 Regulatory Framework for Drugs for Rare Diseases""; ""4 Discovery Research for Rare Diseases and Orphan Product Development""; ""5 Development of New Therapeutic Drugs and Biologics for Rare Diseases""; ""6 Coverage and Reimbursement: Incentives and Disincentives for Product Development""; ""7 Medical Devices: Research and Development for Rare Diseases""

""8 Toward an Integrated Approach to Accelerating Research and Product Development for Rare Diseases""""References""; ""Appendix A: Study Activities""; ""Appendix B: Innovation and the Orphan Drug Act, 1983-2009: Regulatory and Clinical Characteristics of Approved Orphan Drugs""; ""Appendix C: Medicare Part D Coverage and



Reimbursement of Orphan Drugs""; ""Appendix D: Glossary, Abbreviations, and Public Laws""; ""Appendix E: Rare Diseases Clinical Research Network""; ""Appendix F: Advocacy Group Approaches to Accelerating Research and Product Development: Illustrative Examples""

""Appendix G: Committee and Staff Biographies""""Index""

2.

Record Nr.

UNINA9910791122203321

Titolo

Forgetting / / edited by Sergio Della Sala

Pubbl/distr/stampa

New York : , : Psychology Press, , 2010

ISBN

1-136-97086-X

1-136-97087-8

1-282-62957-3

9786612629570

0-203-85164-1

Descrizione fisica

1 online resource (353 p.)

Collana

Current issues in memory

Altri autori (Persone)

Della SalaSergio

Disciplina

153.1/25

Soggetti

Memory

Autobiographical memory

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Book Cover; Title; Copyright; Contents; Contributors; Preface; 1 Forgetting: Preliminary considerations; 2 Forgetting: A historical perspective; 3 A new taxonomy of memory and forgetting; 4 Forgetting in memory models: Arguments against trace decay and consolidation failure; 5 Connectionist models of forgetting; 6 Synaptic plasticity and the neurobiology of memory and forgetting; 7 The functional neuroimaging of forgetting; 8 Sleep and forgetting; 9 Forgetting due to retroactive interference in amnesia: Findings and implications; 10 Accelerated long-term forgetting

11 Aspects of forgetting in psychogenic amnesia12 Autobiographical forgetting, social forgetting, and situated forgetting: Forgetting in context; 13 The role of retroactive interference and consolidation in everyday forgetting; Author index; Subject index



Sommario/riassunto

Memory and forgetting are inextricably intertwined. In order to understand how memory works we need to understand how and why we forget. The topic of forgetting is therefore hugely important, despite the fact that it has often been neglected in comparison with other features of memory. This volume addresses various aspects of forgetting, drawing from several disciplines, including experimental and cognitive psychology, cognitive and clinical neuropsychology, behavioural neuroscience, neuroimaging, clinical neurology, and computational modeling. The first chapters of the book d