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1. |
Record Nr. |
UNINA9910456069203321 |
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Titolo |
The burden of musculoskeletal conditions at the start of the millennium [[electronic resource] ] : a report of a WHO scientific group |
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Pubbl/distr/stampa |
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Geneva, : World Health Organization, 2003 |
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ISBN |
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1-280-04133-1 |
9786610041336 |
92-4-068015-2 |
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Descrizione fisica |
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1 online resource (230 p.) |
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Collana |
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WHO technical report series ; ; v. 919 |
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Disciplina |
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Soggetti |
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Epidemiology |
Musculoskeletal system - Diseases |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di contenuto |
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Contents; 1. Introduction; 2. Global burden of disease; 3. Incidence and prevalence of musculoskeletal conditions; 4. Severity and course of the conditions; 5. Health and economic indicators; 6. Measuring the health impact and economic burden of musculoskeletal conditions on the population; 7. Describing health status and the consequences of illness or injury for the individual; 8. Inventory of published assessment instruments for musculoskeletal conditions; 9. Conclusions and recommendations; Acknowledgements; References |
Annex: Estimates of incidence or prevalence of key musculoskeletal disorders considered for each WHO region |
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Sommario/riassunto |
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To help better prepare nations for the increase in disability brought about by musculoskeletal conditions, a Scientific Group meeting was held to map out the burden of the most prominent musculoskeletal conditions. In particular, the Group gathered data on the incidence and prevalence of rheumatoid arthritis, osteoarthritis, osteoporosis, major limb trauma, and spinal disorders. Data was collected and organized by world region, gender, and age groups to assist with the ongoing WHO Global Burden of Disease 2000 study. The Group also considered what is known about the severity and course of thes |
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2. |
Record Nr. |
UNINA9910139129203321 |
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Titolo |
Neuroinflammation and CNS disorders / / edited by Nicola Woodroofe, Sandra Amor |
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Pubbl/distr/stampa |
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West Sussex, England : , : John Wiley & Sons, , 2014 |
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©2014 |
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ISBN |
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1-118-40654-0 |
1-118-40655-9 |
1-118-40653-2 |
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Edizione |
[First edition.] |
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Descrizione fisica |
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1 online resource (420 p.) |
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Disciplina |
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Soggetti |
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Inflammation - Pathophysiology |
Central nervous system - Diseases - Immunological aspects |
Nervous system - Degeneration - Immunological aspects |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Immune privilege of the brain -- Innate immunity in the CNS : a focus on the myeloid cell -- Adaptive immune responses in the CNS -- Ageing and the immune response in the CNS -- Brain repair : the role of endogenous and transplanted neural stem cells -- Neuroinflammation in Alzheimer's, Parkinson's, and Huntington's diseases -- CNS infections -- Neuroimmunology of amyotrophic lateral sclerosis -- Demyelinating disorders of the CNS -- Other autoimmune disorders : systemic lupus erythematosus, primary Sjogren's syndrome, gluten-related neurological dysfunction, and paraneoplastic neurological syndromes -- Inflammation in the pathogenesis of depression -- Immune responses in the CNS in epilepsy -- Inflammatory mediators and dysfunction of the neurovascular unit following ischaemia reperfusion -- Spinal cord injury -- Immune responses to tumours in the CNS. |
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Sommario/riassunto |
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The last decade has seen an upsurge of information on the role of immune responses in neurodegenerative disorders. In many of these diseases it is still unclear whether the innate and adaptive responses are pathogenic or play a role in repair, and thus understanding their |
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precise roles is key to controlling these diseases by designing immune-therapeutic approaches. The connection between many neurological diseases is the realisation that the immune and nervous systems are inextricable linked, and that perturbations in this delicate balance are involved in many disorders. This has open |
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