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Record Nr. |
UNINA9910455379603321 |
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Autore |
Kielhorn J |
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Titolo |
2-butenal [[electronic resource] /] / first draft prepared by J. Kielborn and I. Mangelsdorf ; and K. Ziegler-Skylakakis |
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Pubbl/distr/stampa |
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Geneva, : World Health Organization, c2008 |
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ISBN |
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1-282-25001-9 |
9786612250019 |
92-4-068367-4 |
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Descrizione fisica |
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1 online resource (55 p.) |
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Collana |
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Concise international chemical assessment document, , 1020-6167 ; ; 74 |
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Altri autori (Persone) |
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MangelsdorfI |
Ziegler-SkylakakisK |
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Disciplina |
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Soggetti |
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Crotonaldehyde - Environmental aspects |
Crotonaldehyde - Toxicology |
Crotonaldehyde - Physiological effect |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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"IPCS, International Programme on Chemical Safety." |
"Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organization, and the World Health Organization, and produced within the framework of the Inter-Organization Programme for the Sound Management of Chemicals." |
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Nota di bibliografia |
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Includes bibliographical references (p. 32-38). |
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Nota di contenuto |
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COVER; COPYRIGHT; TABLE OF CONTENTS; FOREWORD; 1. EXECUTIVE SUMMARY; 2. IDENTITY AND PHYSICAL/CHEMICAL PROPERTIES; 3. ANALYTICAL METHODS; 4. SOURCES OF HUMAN AND ENVIRONMENTAL EXPOSURE; 5. ENVIRONMENTAL TRANSPORT, DISTRIBUTION, TRANSFORMATION, AND ACCUMULATION; 6. ENVIRONMENTAL LEVELS AND HUMAN EXPOSURE; 7. COMPARATIVE KINETICS AND METABOLISM IN LABORATORY ANIMALS AND HUMANS; 8. EFFECTS ON LABORATORY MAMMALS AND IN VITRO TEST SYSTEMS; 9. EFFECTS ON HUMANS; 10. EFFECTS ON OTHER ORGANISMS IN THE LABORATORY AND FIELD; 11. EFFECTS EVALUATION; 12. PREVIOUS EVALUATIONS BY IOMC BODIES; REFERENCES |
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Sommario/riassunto |
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2-Butenal (also known as crotonaldehyde) is an a,-unsaturated aldehyde and consequently a very reactive compound. It is a chemical intermediate used chiefly in the manufacture of sorbates, solvents, and, to a lesser extent, pharmaceutical products and aroma chemicals. This document studies the pharmacokinetics, environmental exposure, chemical toxicology and carcinogenicity of 2-butenal. However, to enable an understanding and evaluation of this aldehyde in the context of environmental health, other aldehydes, such as formaldehyde, acetaldehyde, and acrolein, are mentioned for comparison, where |
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