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1. |
Record Nr. |
UNINA9910455086503321 |
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Autore |
Hosford William F. |
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Titolo |
Mechanical behavior of materials / / William F. Hosford [[electronic resource]] |
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Pubbl/distr/stampa |
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Cambridge : , : Cambridge University Press, , 2010 |
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ISBN |
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1-107-20506-9 |
0-511-81092-X |
0-511-65836-2 |
0-511-65650-5 |
0-511-65565-7 |
0-511-65705-6 |
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Edizione |
[Second edition.] |
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Descrizione fisica |
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1 online resource (xv, 419 pages) : digital, PDF file(s) |
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Disciplina |
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Soggetti |
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Materials - Mechanical properties |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Title from publisher's bibliographic system (viewed on 05 Oct 2015). |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Stress and strain -- Elasticity -- Mechanical testing -- Strain hardening of metals -- Plasticity theory -- Strain rate and temperature dependence of flow stress -- Slip and crystallographic textures -- Dislocation geometry and energy -- Dislocation mechanics -- Mechanical twinning and martenitic shear -- Hardening mechanisms in metals -- Discontinuous and inhomogeneous deformation -- Ductility and fracture -- Fracture mechanics -- Viscoelasticity -- Creep and stress rupture -- Fatigue -- Residual stresses -- Ceramics and glasses -- Polymers -- Composites -- Mechanical working -- Appendix I: Miller indices -- Appendix II: Stereographic representation of orientations. |
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Sommario/riassunto |
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This textbook fits courses on mechanical behavior of materials in mechanical engineering and materials science and includes numerous examples and problems. It emphasizes quantitative problem solving. This text differs from others because the treatment of plasticity emphasizes the interrelationship of the flow, effective strain, and effective stress and their use in conjunction with yield criteria to solve problems. The treatment of defects is new, as is the analysis of |
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particulate composites. Schmid's law is generalized for complex stress states. Its use with strains allows for prediction of R-values for textures. Of note is the treatment of lattice rotations related to deformation textures. The chapter on fracture mechanics includes coverage of Gurney's approach. Among the highlights in this new edition are the treatment of the effects of texture on properties and microstructure in Chapter 7, a new chapter (12) on discontinuous and inhomogeneous deformation, and the treatment of foams in Chapter 21. |
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2. |
Record Nr. |
UNINA9910784654703321 |
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Autore |
Kenakin Terrence P |
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Titolo |
A pharmacology primer [[electronic resource] ] : theory, applications, and methods / / Terry Kenakin |
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Pubbl/distr/stampa |
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Burlington, MA ; ; London, : Academic Press, c2006 |
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ISBN |
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1-280-70765-8 |
9786610707652 |
0-08-046530-7 |
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Edizione |
[2nd ed.] |
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Descrizione fisica |
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1 online resource (319 p.) |
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Disciplina |
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Soggetti |
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Pharmacology |
Drugs |
Chemicals - Physiological effect |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Previous ed.: London: Elsevier, 2004. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Front cover; A PHARMACOLOGY PRIMER THEORY, APPLICATION, AND METHODS; Copyright page; Foreword to Second Edition; Foreword to First Edition; Table of contents; Chapter 1. What Is Pharmacology?; 1.1 About This Book; 1.2 What Is Pharmacology?; 1.3 The Receptor Concept; 1.4 Pharmacological Test Systems; 1.5 The Nature of Drug Receptors; 1.6 Pharmacological Intervention and the Therapeutic Landscape; 1.7 System-independent Drug Parameters: Affinity and |
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Efficacy; 1.8 What Is Affinity?; 1.9 The Langmuir Adsorption Isotherm; 1.10 What Is Efficacy?; 1.11 Dose-response Curves |
1.12 Chapter Summary and Conclusions1.13 Derivations: Conformational Selections as a Mechanism of Efficacy; References; Chapter 2. How Different Tissues Process Drug Response; 2.1 Drug Response as Seen Through the ''Cellular Veil''; 2.2 The Biochemical Nature of Stimulus-response Cascades; 2.3 The Mathematical Approximation of Stimulus-response Mechanisms; 2.4 System Effects on Agonist Response: Full and Partial Agonists; 2.5 Differential Cellular Response to Receptor Stimulus; 2.6 Receptor Desensitization and Tachyphylaxis; 2.7 The Measurement of Drug Activity |
2.8 Advantages and Disadvantages of Different Assay Formats2.9 Drug Concentration as an Independent Variable; 2.10 Chapter Summary and Conclusions; 2.11 Derivations; References; Chapter 3. Drug-Receptor Theory; 3.1 About This Chapter; 3.2 Drug-Receptor Theory; 3.3 The Use of Mathematical Models in Pharmacology; 3.4 Some Specific Uses of Models in Pharmacology; 3.5 Classical Model of Receptor Function; 3.6 The Operational Model of Receptor Function; 3.7 Two-state Theory; 3.8 The Ternary Complex Model; 3.9 The Extended Ternary Model; 3.10 Constitutive Receptor Activity |
3.11 The Cubic Ternary Complex Model3.12 Chapter Summary and Conclusions; 3.13 Derivations; References; Chapter 4. Pharmacological Assay Formats: Binding; 4.1 The Structure of This Chapter; 4.2 Binding Theory and Experiment; 4.3 Complex Binding Phenomena: Agonist Affinity from Binding Curves; 4.4 Experimental Prerequisites for Correct Application of Binding Techniques; 4.5 Chapter Summary and Conclusions; 4.6 Derivations; References; Chapter 5. Agonists: The Measurement of Affinity and Efficacy in Functional Assays; 5.1 Functional Pharmacological Experiments |
5.2 The Choice of Functional Assays5.3 Recombinant Functional Systems; 5.4 Functional Experiments: Dissimulation in Time; 5.5 Experiments in Real Time Versus Stop Time; 5.6 The Measurement of Agonist Affinity in Functional Experiments; 5.7 Estimates of Relative Efficacy of Agonists in Functional Experiments; 5.8 Chapter Summary and Conclusions; 5.9 Derivations; References; Chapter 6. Orthosteric Drug Antagonism; 6.1 Introduction; 6.2 Kinetics of Drug-Receptor Interaction; 6.3 Surmountable Competitive Antagonism; 6.4 Noncompetitive Antagonism; 6.5 Agonist-Antagonist Hemi-equilibria |
6.6 Resultant Analysis |
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Sommario/riassunto |
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The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments.*Over 30 new figures and tables*More human interest information to provide readers with historical facts on pharmacology research*New section on therapeutics to help identify diseases and drug treatments*New section on new biological concepts relevant to pharmacological researc |
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