1.

Record Nr.

UNINA9910454834003321

Autore

Nagradova N. K (Natalia Konstantinovna)

Titolo

Foldases catalyzing the formation and isomerization of disulfide bonds in proteins [[electronic resource] /] / Natalya K. Nagradova

Pubbl/distr/stampa

New York, : Nova Biomedical Books, c2009

ISBN

1-60741-689-1

Descrizione fisica

1 online resource (85 p.)

Disciplina

572/.633

Soggetti

Protein disulfide isomerase

Protein folding

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references (p. [61]-68) and index.

Nota di contenuto

""FOLDASES CATALYZING THE FORMATION AND ISOMERIZATION OF DISULFIDE BONDS IN PROTEINS""; ""Contents""; ""Preface ""; ""Introduction ""; ""Eukaryotic Protein Disulfide Isomerase (PDI)""; ""1.1. The Role of Protein Disulfide Isomerase in the Endoplasmic Reticulum""; ""1.2. Modular Organization of the PDI Molecule and the Role of Different Domains""; ""1.3. Functional Properties of PDI Active Centers. The pKa Values of Essential Cysteine Residues ""; ""1.4. Disulfide Isomerization: The Essential Function of PDI ""; ""1.5. Dithiol Oxidation Catalyzed by PDI ""

""1.6. The Role of Glutathione in Oxidative Protein Folding in Endoplasmic Reticulum """"Disulfide Bond Formation and Isomerization in Prokaryotes ""; ""2.1. A Pathway for Disulfide Bond Formation in the Periplasm ""; ""2.2. Similarities in Prokaryotic and Eukaryotic Disulfide Bond-Forming Pathways ""; ""2.3. A Pathway for Disulfide Bond Isomerization in the Periplasm ""; ""Conclusion ""; ""References ""; ""Index ""