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1. |
Record Nr. |
UNINA9910463370603321 |
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Titolo |
Iron-sulfur clusters in chemistry and biology / / edited by Tracey Rouault |
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Pubbl/distr/stampa |
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Berlin, [Germany] ; ; Boston, [Massachusetts] : , : De Gruyter, , 2017 |
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©2017 |
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ISBN |
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Edizione |
[2. Aufl.] |
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Descrizione fisica |
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1 online resource (466 pages) : illustrations |
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Collana |
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Iron-Sulfur Clusters in Chemistry and Biology ; ; Volume 1 |
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Disciplina |
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Soggetti |
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Trace elements in nutrition |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Frontmatter -- Preface -- Tracey A. Rouault biography -- Contents -- List of contributing authors -- 1. Iron-sulfur proteins: a historical perspective / Bonomi, Francesco / Rouault, Tracey A. -- 2. Chemistry of iron-sulfur clusters / Ichiye, Toshiko -- 3. From the quantum chemistry of iron-sulfur clusters to redox energetics and reaction pathways in metalloenzymes / Noodleman, Louis -- 4. Bioinorganic spectroscopy of iron sulfur proteins- an overview / Guo, Yisong / Li, Jikun -- 5. Quantitative interpretation of EPR spectroscopy with applications for iron-sulfur proteins / Petasis, Doros T. / Hendrich, Michael P. -- 6. The utility of Mössbauer spectroscopy in eukaryotic cell biology and animal physiology / Chakrabarti, Mrinmoy / Lindahl, Paul A. -- 7. The interstitial carbide of the nitrogenase M-cluster: insertion pathway and possible function / Sickerman, Nathaniel S. / Ribbe, Markus / Hu, Yilin -- 8. The iron-molybdenum cofactor of nitrogenase / Spatzal, Thomas / Andrade, Susana L. A. / Einsle, Oliver -- 9. Biotin synthase: a role for iron-sulfur clusters in the radical-mediated generation of carbon-sulfur bonds / Jarrett, Joseph T. -- 10. Molybdenum-containing iron-sulfur enzymes / Hille, Russ -- 11. The role of iron-sulfur clusters in the biosynthesis of the lipoyl cofactor / Lanz, Nicholas D. / Booker, Squire J. -- 12. Iron-sulfur clusters and molecular oxygen: function, adaptation, degradation, and repair / Nicolet, Yvain / Fontecilla-Camps, Juan C. -- 13. Reactivity of iron- |
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sulfur clusters with nitric oxide / Dodd, Erin L. / Crack, Jason C. / Thomson, Andrew J. / Le Brun, Nick E. -- Index |
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Sommario/riassunto |
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This volume on iron-sulfur proteins includes chapters that describe the initial discovery of iron-sulfur proteins in the 1960s to elucidation of the roles of iron sulfur clusters as prosthetic groups of enzymes, such as the citric acid cycle enzyme, aconitase, and numerous other proteins, ranging from nitrogenase to DNA repair proteins. The capacity of iron sulfur clusters to accept and delocalize single electrons is explained by basic chemical principles, which illustrate why iron sulfur proteins are uniquely suitable for electron transport and other activities. Techniques used for detection and stabilization of iron-sulfur clusters, including EPR and Mossbauer spectroscopies, are discussed because they are important for characterizing unrecognized and elusive iron sulfur proteins. Recent insights into how nitrogenase works have arisen from multiple advances, described here, including studies of high-resolution crystal structures. |
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2. |
Record Nr. |
UNINA9910453995503321 |
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Autore |
Montague Terrence J. <1945-> |
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Titolo |
Patients first [[electronic resource] ] : closing the health care gap in Canada / / Terrence J. Montague |
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Pubbl/distr/stampa |
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Mississauga, Ont., : Wiley, c2004 |
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ISBN |
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0-470-67522-5 |
1-282-03059-0 |
9786612030598 |
0-470-15748-8 |
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Descrizione fisica |
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1 online resource (264 p.) |
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Disciplina |
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Soggetti |
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Medical personnel and patient - Canada |
Medical care - Canada |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references (p. 239-246) and index. |
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Nota di contenuto |
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Title; Copyright; Contents; Foreword; Foreword; Acknowledgements; Introduction; Part 1: The Theory; Part 2: The Practice-Patient Health Management (PHM); Part 3: What Have We Learned So Far?; Part 4: Vision for the Future; Appendices; Bibliography; Index |
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Sommario/riassunto |
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PATIENTS FIRSTCLOSING THE HEALTH CARE GAP IN CANADA""This book is a must read for those who are interested in our health care system and who want to make it better. Dr. Montague provides an interesting overview of his journey through hospital wards, clinical trials, patient registries, patient health management and chronic disease management programs. Drawing on his diverse and unique background, he gives an important history of the past, analysis of the present and a glimpse of our future.""--David Johnstone, MDPresident, Canadian Cardiovascular Society |
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