1.

Record Nr.

UNINA9910453676603321

Titolo

Nuclear receptors as molecular targets for cardiometabolic and central nervous system diseases [[electronic resource] /] / edited by J.L. Junien and B. Staels

Pubbl/distr/stampa

Amsterdam ; ; Washington, DC, : IOS Press, c2008

ISBN

661178618X

1-281-78618-7

9786611786182

1-4356-7800-1

600-00-0636-5

1-60750-327-1

Descrizione fisica

1 online resource (128 p.)

Collana

Solvay Pharmaceuticals Conferences ; ; v. 8

Altri autori (Persone)

JunienJean-Louis

StaelsB

Disciplina

615.7

615.8/95

Soggetti

Central nervous system - Diseases

Heart - Diseases

Nuclear receptors (Biochemistry)

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

"Contains papers from the Eight Solvay Pharmaceuticals Conference on Nuclear Receptors as Molecular Targets for Cardiometabolic and Central Nervous System Diseases held in Nice (France) April 11-13, 2007" -- p. vi.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Title page; Preface; List of Contributors; Contents; Conference Preface and Keynote Lecture; Conference Preface; Keynote Lecture - An Introduction to the Nuclear Receptor Superfamily; Metabolic Control by LXR; Regulation of Cardiac Energetic by the Orphan Nuclear Receptors ERRalfa and gamma; FXR and Bile Acids: Critical Modulators of Metabolism; The Role of PPARs in Human Prediabetes; New Insights in the Role of the Intestine in Reverse Cholesterol Transport; NR4A Nuclear Receptors in the Vessel Wall; Cholesterol: Novel Target in the



Treatment of Alzheimer's Disease?

PPARgamma-Mediated Effects in CNS DisordersMolecular Biology of Circadian Rhythms and Cardiometabolic Disease: Role of the Orphan Nuclear Receptor Rev-erbalfa; Author Index

Sommario/riassunto

Focuses on the mechanistic involvement of nuclear receptors in cardiological, metabolic and neurological disorders. This book also focuses on possible explanation of pathways involved in pathogenesis, on susceptibility to and prevention of metabolic and neurological disorders, and on the aspects of drug finding.