1.

Record Nr.

UNINA9910453498303321

Autore

Cordes Eugene H

Titolo

Hallelujah moments : tales of drug discovery / / Eugene H. Cordes

Pubbl/distr/stampa

New York, New York : , : Oxford University Press, , 2014

©2014

ISBN

0-19-756286-8

0-19-933716-0

0-19-933715-2

Descrizione fisica

1 online resource (258 p.)

Collana

Oxford scholarship online

Disciplina

615.19

Soggetti

Drug development - History

Drugs - Research

Pharmaceutical chemistry

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Includes index.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Cover; Contents; Preface; Acknowledgments; 1. Seduced by Drug Discovery; 2. The Small Molecules of Life; 3. Proteins: Molecular Wonders in Three Dimensions; 4. Proteins Perform Multiple Functions: Enzymes, Receptors, Ion Channel Proteins; 5. Drug Discovery and Development: The Road from an Idea to Promoting Human Health; 6. Finasteride: The Gary and Jerry Show; 7. Basic Research, Snake Venoms, and ACE Inhibitors: Ondetti, Cushman, and Patchett; 8. Statins: Protection Against Heart Attacks and Strokes-Hallelujah!; 9. Th e Perils of Primaxin; 10. Avermectins: Molecules of Life Battle Parasites

11. Fludalanine: Nice Try But No Hallelujah12. Diabetes Breakthroughs: Januvia and Janumet; NOTES; INDEX; A; B; C; D; E; F; G; H; I; J; K; L; M; N; O; P; Q; R; S; T; U; V; W; X; Y; Z

Sommario/riassunto

Pharmeceutical drug discovery has wide-reaching and obvious effects on the lives of people everywhere, and yet the general public knows very little about the way in which these important products are conceived. We rely on pharmaceuticals to keep us healthy in countless ways, with almost no understanding of the process behind the creation of the drugs we use. In this book, Eugene Cordes reveals just how some



of the most important and influential drugs are made. He shares his firsthand knowledge of the drug-discovery world, having spent a long and distinguished career on both the academic and industrial side of pharmaceutical research.