Novel cancer-related biomarkers [[electronic resource] /] / editors, Viktor Magdolen ... [et al.]

• Record Nr.: UNINA9910452896003321
• Pubbl/distr/stampa: Berlin, : De Gruyter, 2012
• ISBN: 3-11-048153-7; 3-11-030366-3
• Descrizione fisica: 1 online resource (242 p.)
• Collana: Kallikrein-related peptidases ; ; v. 2
• Altri autori (Persone): MagdolenViktor
• Soggetti: Tumor markers; Cancer - Diagnosis; Electronic books.
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Frontmatter -- Preface -- List of contributing authors -- Table of Contents -- Introduction to Volume 2: Kallikrein-related Peptidases. Novel Cancer-related Biomarkers / Schmitt, Manfred / Sommerhoff, Christian P. / Fritz, Hans / Magdolen, Viktor -- 1 Pathophysiology of Kallikrein-related Peptidases in Lung Cancer / Heuzé-Vourc'H, Nathalie / Courty, Yves -- 2 Clinical Relevance of Kallikrein-related Peptidases in Gastric and Colorectal Cancer / Talieri, Maroulio / Devetzi, Marina / Schmitt, Manfred -- 3 Pathophysiology of Kallikrein-related Peptidases in Head and Neck Cancer / Jiang, Rong / Shi, Zonggao / Johnson, Jeffrey / Stack, M. Sharon -- 4 PSA (Prostate-Specific Antigen) and other Kallikrein-related Peptidases in Prostate Cancer / Koistinen, Hannu / Stenman, Ulf-Håkan -- 5 Cellular Model Systems to Study the Tumor Biological Role of Kallikrein-related Peptidases in Ovarian and Prostate Cancer / Dong, Ying / Loessner, Daniela / Sieh, Shirly / Taubenberger, Anna / Fuhrman-Luck, Ruth A. / Magdolen, Viktor / Hutmacher, Dietmar W. / Clements, Judith A. -- 6 Clinical Relevance of Kallikrein-related Peptidases in Breast Cancer / Schmitt, Manfred / Dorn, Julia / Kiechle, Marion / Diamandis, Eleftherios P. / Luo, Liu-Ying -- 7 Clinical Relevance of Kallikrein-related Peptidases in Ovarian Cancer / Dorn, Julia / Milou, Valentina / Kulasingam, Vathany / Schmalfeldt, Barbara / Diamandis, Eleftherios P. / Schmitt, Manfred -- ; 8 microRNAs: A New Control Mechanism for Kallikrein-related Peptidases in Kidney and Other Cancers / Yousef, George M. / White, Nicole M.A. -- 9 Genomic Instability of the KLK-locus in Cancer / Bayani, Jane / Diamandis, Eleftherios P. -- 10 Kallikrein-related Peptidases as Biomarkers in Personalized Cancer Medicine / Mavridis, Konstantinos / Schmitt, Manfred / Scorilas, Andreas -- Index
• Sommario/riassunto: Various KLK proteins and their encoding genes have attracted increased attention among scientists and clinicians worldwide since they represent very interesting and functionally distinct biomarkers, particularly, in cancer. This book reviews the role of kallikrein-related peptidases (KLKs) in a wide range of cancers, including lung, prostate, breast and ovarian cancer. It provides clinicians, physician scientists and researchers with a comprehensive overview on the clinical relevance of KLK expression in various malignancies.