1.

Record Nr.

UNINA9910451815103321

Autore

Bucala Richard

Titolo

Fibrocytes in health and disease [[electronic resource] /] / Richard Bucala

Pubbl/distr/stampa

Singapore, : World Scientific Pub. Co., 2012

ISBN

1-280-66943-8

9786613646361

981-4343-72-2

Descrizione fisica

1 online resource (335 p.)

Disciplina

611.0181

Soggetti

Fibroblasts

Connective tissues - Diseases

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Contents; Preface; Contributors; Chapter 1. Hematopoietic Origin of Fibrocytes Mehrdad Abedi; 1.1. Introduction; 1.2. Structure of Bone Marrow; 1.3. Marrow-Derived Fibroblasts; 1.4. Origin of Fibroblasts in Tissue; 1.5. Fibrocytes; 1.6. What is the Relation between Macrophages and Circulating Fibroblasts Precursors?; 1.7. Perspective; References; Chapter 2. Fibrocytes and Collagen-Producing Cells of the Peripheral Blood Richard H. Gomer and Darrell Pilling; 2.1. Introduction: Fibrocytes Precursors Originate in Bone Marrow, and Exist in Blood

2.2. The Chemokine CXCL12 Attracts Circulating Fibrocyte Precursors to Sites of Injury2.3. Identification of Circulating CCPCs in the Blood; 2.4. Pulmonary Fibrosis Patients have Abnormally High Numbers of CCPCs; 2.5. Scleroderma Patients have Abnormally High Numbers of CCPCs; 2.6. Differences between CCPCs from Scleroderma Patients and Controls; 2.7. Patients with Chronic Asthma have Abnormally High Numbers of CCPCs; 2.8. CCPCs in Rheumatoid Arthritis Patients; 2.9. The Number of CCPCs Increases with Age; 2.10. The Number of CCPCs Increases in an Animal Injury Model

2.11. Summary and Future DirectionsAcknowledgements; References; Chapter 3. Regulatory Pathways of Fibrocyte Development Darrell Pilling



and Richard H. Gomer; 3.1. Introduction; 3.2. Inhibition of Initial Fibrocyte Differentiation by Fcγ Receptor Ligation; 3.3. Inhibition of Initial Fibrocyte Differentiation by Cytokines; 3.4. Profibrotic Cytokines Promote Fibrocyte Differentiation; 3.5. Regulation of Mature Fibrocyte Differentiation; References; Chapter 4. Fibrocyte Differentiation Pathways Ellen C. Keeley, Borna Mehrad and Robert M. Strieter; 4.1. Introduction

4.2. Fibrocyte Differentiation along Mesenchymal Lineages4.2.1. Myofibroblasts; 4.2.2. Adipocytes; 4.2.3. Osteoblasts and Chondrocytes; 4.3. Fibrocytes can be Reprogrammed to Modify the Fibroproliferative Response; 4.4. Factors that Influence Differentiation of Fibrocytes from their Precursors; 4.5. Conclusion; References; Chapter 5. Immunoregulation of Fibrocyte Differentiation Matthias Mack, Marianne Niedermeier and Barbara Reich; 5.1. Detection and Origin of Fibrocytes; 5.2. Interaction of Monocytes with CD4+ T Cells Enables Differentiation of Fibrocytes

5.3. Cytokines and CD4+ T Cell Phenotypes Regulate Fibrocyte Differentiation5.4. Influence of Serum on Fibrocyte Differentiation; 5.5. Proliferation of Fibrocytes?; 5.6. Migration of Fibrocytes; 5.7. How Fibrocytes Affect CD4+ T Cells; 5.8. Conclusion; References; Chapter 6. The Role of Fibrocytes in Wound Repair and Hypertrophic Scarring Abelardo Medina, Jie Ding, Moein Momtazi, and Edward E. Tredget; 6.1. Introduction; 6.2. Dysregulated Repair of the Extracellular Matrix of Hypertrophic Scars; 6.3. Dysregulated Apoptosis in Hypertrophic Scar

6.4. Increased Levels of the Profibrotic Growth Factors TGF-β and CTGF in Hypertrophic Scarring

Sommario/riassunto

This volume provides a comprehensive and multidisciplinary overview of fibrocytes, written by the main researchers in the field. It is aimed at a broad audience of scientists and clinicians with an interest in the role of circulating fibrocytes in the etiopathogenesis of different fibrosing disorders, atherosclerosis, autoimmunity, and cancer.



2.

Record Nr.

UNISALENTO991001346919707536

Autore

Albeverio, Sergio

Titolo

Singular perturbations of differential operators : solvable Schrodinger type operators / S. Albeverio, P. Kurasov

Pubbl/distr/stampa

Cambridge : Cambridge University Press, 2000

ISBN

052177912X

Descrizione fisica

xiv, 429 p. ; 23 cm

Collana

London Mathematical Society lecture note series, 0076-0552 ; 271

Classificazione

AMS 35J10

Altri autori (Persone)

Kurasov, P.

Altri autori (Enti)

London Mathematical Society

Disciplina

515.353

Soggetti

Perturbation (Mathematics)

Schrodinger operator

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Includes bibliographical references and index