International Responsibility Today : Essays in Memory of Oscar Schachter / / edited by Maurizio Ragazzi

• Record Nr.: UNINA9910451453403321
• Pubbl/distr/stampa: Leiden; ; Boston : , : Brill | Nijhoff, , 2005
• ISBN: 1-280-86877-5; 9786610868773; 1-4294-5336-2; 90-474-0770-9; 1-4337-0588-5
• Descrizione fisica: 1 online resource (548 p.)
• Disciplina: 342.08/8
• Soggetti: Government liability (International law); International right; Responsibility; State liability; Electronic books.
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: Editor's Dedication, -- Editor's Preface, -- Oscar Schachter's Summary Biography, -- Oscar Schachter's Select Bibliography, -- List of Contributors, -- Memorial List, -- Table of Cases, -- Table of Documents, -- List of Abbreviations, -- Part One , State Responsibility (General Issues) , -- Chapter One , The Essence of the Structure of International Responsibility, Chittharanjan Felix Amerasinghe , -- Chapter Two , Legal Injury: The Tip of the Iceberg in the Law of State Responsibility?, Julio Barboza , -- Chapter Three , State Crime: Looking at Municipal Experience with Organizational Crime, David D. Caron , -- Chapter Four , Do States Have a Duty to Ensure Compliance with Obligations Erga Omnes by Other States?, Giorgio Gaja , -- Chapter Five , Diplomacy and State Responsibility, Kazuhiro Nakatani , -- Chapter Six , Controlling Countermeasures, Mary Ellen O'Connell , -- Chapter Seven , International Crimes and State Responsibility, Pemmaraju Sreenivasa Rao , -- Chapter Eight , International ; Responsibility and the Principle of Causality, François Rigaux , -- Chapter Nine , A Plea for 'Reconstruction' of International Responsibility Based on the Notion of Legal Injury, Brigitte Stern , -- Chapter Ten , The Art of Apology, Sir Arthur Watts , -- Chapter Eleven , Revisiting the International Law Commission's Draft Articles on State Responsibility, Chusei Yamada , -- Chapter Twelve , Does the Prospect of Incurring Responsibility Improve the Observance of International Law?, Karl Zemanek , -- Part Two , State Responsibility (Particular Concerns) , -- Chapter Thirteen , War Against Terrorism Extra Moenia, Self-defence and Responsibility: A Pure Juridical Approach, Giovanni Battaglini , -- Chapter Fourteen , International Responsibility of the State and Individual Criminal Responsibility in the International Protection of Human Rights, Héctor Gros Espiell , -- Chapter Fifteen , The Protection of Shareholders under International Law: Making State Responsibility more Accessible, Francisco Orrego-Vicuña , -- Chapter Sixteen , The Limits of International Responsibility in the Protection of Foreign Investments, Vratislav Pechota , -- Chapter Seventeen , International Responsibility and Cooperation for Development, Jorge Peirano , -- Chapter Eighteen , Italy's Non-belligerency during the Iraqi War, Natalino Ronzitti , -- Chapter Nineteen , Some Remarks on International Responsibility in the Field of Environmental Protection, Tullio Scovazzi , -- Chapter Twenty , The International Law Commission's Articles on State Responsibility and the Settlement of Disputes, Tullio Treves , -- Chapter Twenty-One , Humanitarian Intervention and International Responsibility, Budislav Vukas , -- Part Three , State Responsibility and the Courts , -- Chapter Twenty-Two , Just Satisfaction under the European Convention on Human Rights, Rudolf Bernhardt , -- Chapter Twenty-Three , Complementarity between State Responsibility and Individual Responsibility for Grave Violations of Human Rights: The Crime of State Revisited, Antônio Cançado Trindade , -- Chapter Twenty-Four , The International Court of Justice: Selected Issues of State Responsibility, Dame Rosalyn Higgins , -- Chapter Twenty-Five , Registration of Foreign Judgments under the European Convention of Human Rights and the Law of International Responsibility, Laura Picchio Forlati , -- Chapter Twenty-Six , Decisions of the International Court of Justice and the New Law of State Responsibility, Shabtai Rosenne , -- Chapter Twenty-Seven , Injured and Non-injured States before the International Court of Justice, Hugh Thirlway , -- Chapter Twenty-Eight , The Oil Platforms Case before the International Court of Justice: A Non-case of International Responsibility, Daphné Richemond and Prosper Weil , -- Part Four , Responsibility of International Organizations and Other Non-State Entities , -- Chapter Twenty-Nine , Objective Meaning of Constituent Instruments and Responsibility of International Organizations, Robert Araujo , -- Chapter Thirty , The Responsibility of States for the Acts of International Organizations, Ian Brownlie , -- Chapter Thirty-One , The International Responsibility of the United Nations for Injuries Resulting from Non-Military Enforcement Measures, Christian Dominicé , -- Chapter Thirty-Two , The Definition of 'International Organization' in the International Law Commission's Current Project on the Responsibility of International Organizations, Maurice Mendelson , -- Chapter Thirty-Three , Non-State Actors: Areas of International Responsibility in Need of Further Exploration, Emmanuel Roucounas , -- Chapter Thirty-Four , Responsibility of International Organizations: Does the European Community Require Special Treatment?, Stefan Talmon , -- Chapter Thirty-Five , State Responsibility for Private Actors: An Old Problem of Renewed Relevance, Rüdiger Wolfrum , -- Chapter Thirty-Six , The Responsibility of States Members of an International ; Organization for its Conduct as a Result of Membership or their Normal Conduct Associated with Membership, Sienho Yee , -- Bibliography, -- Index, -- Memorial List.
• Sommario/riassunto: The law of international responsibility, a classic area of investigation in international law, has been attracting an ever increasing interest in recent times, as reflected also in the work of the International Law Commission on State responsibility and on responsibility of international organizations. The exploration of current trends in this important area is therefore an appropriate and timely subject for a book in memory of Oscar Schachter, a former United Nations official, Columbia Law School professor, ASIL President, and international lawyer of world-wide reputation, who died in December 2003. The editor of the book has assembled a team of thirty-six prominent international lawyers belonging to twenty different nationalities to write about different aspects of the law of international responsibility, from general issues to specific areas of the law (including responsibility before international courts and tribunals), with respect to both the law of State responsibility and responsibility of international organizations and other non-State actors. The result of this effort is a monographic volume (enriched by a biography and a list of publications of Oscar Schachter, and accompanied by a bibliography of all the works cited in the various contributions and an index for easier consultation), which will be of interest not only to the many admirers and friends of Oscar Schachter around the world, but also, more broadly, to international law academics and practitioners.

The necessity of prayer / / E. M. Bounds

• Record Nr.: UNINA9910136508903321
• Autore: Bounds E. M.
• Pubbl/distr/stampa: [Place of publication not identified] : , : Dancing Unicorn Books, , 2016
• ISBN: 1-5154-0994-5
• Descrizione fisica: 1 online resource (79 p.)
• Disciplina: 248.32
• Soggetti: Prayer; Prayer - Biblical teaching; Prayer - Christianity
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di contenuto: Foreword; Prayer and Faith; Prayer and Trust; Prayer and Desire; Prayer and Fervency; Prayer and Importunity; Prayer and Importunity (Continued); Prayer and Character and Conduct; Prayer and Obedience; Prayer and Obedience (Continued); Prayer and Vigilance; Prayer and the Word of God; Prayer and the Word of God (Continued); Prayer and the House of God
• Sommario/riassunto: In any study of the principles, and procedure of prayer, of its activities and enterprises, first place, must, of necessity, be given to faith. It is the initial quality in the heart of any man who essays to talk to the Unseen. He must, out of sheer helplessness, stretch forth hands of faith. He must believe, where he cannot prove. In the ultimate issue, prayer is simply faith, claiming its natural yet marvellous prerogatives - faith taking possession of its illimitable inheritance. True godliness is just as true, steady, and persevering in the realm of faith as it is in the province of prayer

La parcelle dans tous ses états / / Florence Bourillon, Corinne Jaquand

• Record Nr.: UNINA9910591045203321
• Autore: Bidaud Camille
• Pubbl/distr/stampa: Rennes, : Presses universitaires de Rennes, 2022
• ISBN: 2-7535-8724-8
• Descrizione fisica: 1 online resource (262 p.)
• Collana: Histoire
• Altri autori (Persone): BocquetDenis; BourillonFlorence; ErrardPaul-Édouard; GressetPhilippe; GrudetIsabelle; JaquandCorinne; JourdheuilAnne-Laure; LaffontJean-Luc; Lambert-BressonMichèle; LecatPaul; Le BourhisEric; PerlussPreston; PugetJulien; SchoonbaertSylvain; SecciClaudio; SowaCharline; ThiardPhilippe
• Soggetti: Urban Studies; History; morphologie urbaine; zonage; foncier; remembrement
• Lingua di pubblicazione: Francese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Sommario/riassunto: La parcelle en ville est un objet historique qui s’inscrit dans le temps long sous diverses appellations. À la fois projection au sol d’un rapport de propriété légal ou coutumier et « petite partie d’un tout » à des fins d’exploitation et d’investissement, elle est propice aux approches pluridisciplinaires. Son étude renvoie en effet à la question cruciale du changement urbain, mais aussi aux idéologies politiques et modernistes à l’encontre du droit de propriété qui ont pu entraîner sa remise en cause au xxe siècle, comme en URSS et dans les États socialistes ou dans les ensembles d’habitat collectif de l’entre-deux-guerres et des Trente Glorieuses. À rebours, elle constitue un enjeu prégnant dans les projets urbains contemporains, sans que d’ailleurs les discours développés à son sujet ne fassent toujours l’objet de questionnements approfondis. Cet ouvrage se propose de reconstituer l’histoire longue de la parcelle car elle est susceptible de rendre compte, à bien des égards, des transformations contemporaines.

Insomnia and beyond - Exploring the therapeutic potential of orexin receptor antagonists

• Record Nr.: UNINA9910136406903321
• Autore: Michel Alexander Steiner
• Pubbl/distr/stampa: Frontiers Media SA, 2014
• Descrizione fisica: 1 online resource (219 p.)
• Collana: Frontiers Research Topics
• Soggetti: Neurology and clinical neurophysiology
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Sommario/riassunto: Orexin/hypocretin neuropeptides, produced by a few thousand neurons in the lateral hypothalamus, are of critical importance for the control of vigilance and arousal of vertebrates, from fish to amphibians, birds and mammals. Two orexin peptides, called orexin-A and orexin-B, exist in mammals. They bind with different affinities to two distinct, widely distributed, excitatory G-protein- coupled receptors, orexin receptor ; type 1 and type 2 (OXR-1/2). The discovery of an OXR mutation causing canine narcolepsy, the narcolepsy-like phenotype of orexin peptide knockout mice, and the orexin neuron loss associated with human narcoleptic patients laid the foundation for the discovery of small molecule OXR antagonists as novel treatments for sleep disorders. Proof of concept studies from Glaxo Smith Kline, Actelion Pharmaceuticals Ltd. and Merck have now consistently demonstrated the efficacy of dual OXR antagonists (DORAs) in promoting sleep in rodents, dogs, non-human primates and humans. Some of these antagonists have completed late stage clinical testing in primary insomnia. Orexin drug discovery programs have also been initiated by other large pharmaceutical companies including Hoffmann La Roche, Novartis, Eli Lilly and Johnson & Johnson. Orexins are increasingly recognized for orchestrating the activity of the organism's arousal system with appetite, reward and stress processing pathways. Therefore, in addition to models of insomnia, pharmacological effects of DORAs have begun to be investigated in rodent models of addiction, depression and anxiety. The first clinical trials in diabetic neuropathy, migraine and depression have been initiated with Merck's MK-6096 (www.clinicaltrials.gov). Whereas the pharmacology of DORAs is established for their effects on wakefulness, pharmacological effects of selective OXR-1 or OXR-2 antagonists (SORAs) have remained less clear. From an evolutionary point of view, the OXR-2 was expressed first in most vertebrate lineages, whereas the OXR-1 is believed to result from a gene duplication event, when mammals emerged. Yet, both receptors do not have redundant function. Their brain expression pattern, their intracellular signaling, as well as their affinity for orexin-A and orexin-B differs. During the past decade most preclinical research on selective OXR-1 antagonism was performed with SB-334867. Only in recent years, other selective OXR-1 and OXR-2 antagonists with optimized selectivity profiles and pharmacokinetic properties have been discovered, and phenotypes of OXR-1 and OXR-2 knockout mice were described. The present Research Topic (referred to in the Editorial as "special topics issue") comprises submissions of original research manuscripts as well as reviews, directed towards the neuropharmacology of OXR antagonists. The submissions are preclinical papers dealing with dual and/or selective OXR antagonists that shed light on the differential contribution of endogenous orexin signaling through both OXRs for cellular, physiological and behavioral processes. Some manuscripts also report on convergence or divergence of DORA vs. SORA effects with phenotypes expressed by OXR-1 or OXR-2 knockout animals. Ultimately these findings may help further define the potential of DORAs and SORAs in particular therapeutic areas in insomnia and beyond insomnia.