1.

Record Nr.

UNINA9910451287703321

Autore

Kuus Merje

Titolo

Geopolitics reframed [[electronic resource] ] : security and identity in Europe's eastern enlargement / / Merje Kuus

Pubbl/distr/stampa

New York, : Palgrave Macmillan, 2007

ISBN

1-281-36286-7

9786611362867

0-230-60549-4

Edizione

[1st ed.]

Descrizione fisica

1 online resource (222 pages)

Collana

New visions in security

Classificazione

89.71

Disciplina

327.437

Soggetti

Geopolitics - Europe, Central

Geopolitics - Europe, Eastern

National security - Europe, Central

National security - Europe, Eastern

Electronic books.

Europe, Central Politics and government 1989-

Europe, Eastern Politics and government 1989-

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references (p. [123]-204) and index.

Nota di contenuto

Cover; Contents; List of Figures; Preface; Acknowledgments; 1 The Plasticity of Geopolitics; 2 Inscribing Europeanness, Erasing Eastness; 3 Civilizational Geopolitics; 4 Sovereignty for Security?; 5 Cultural Geopolitics and Cultured Geopoliticians; 6 The Ritual of Listening to Foreigners; 7 How Many Threats and How Many Europes?; Notes; Bibliography; Index

Sommario/riassunto

This book traces the shifting meanings of security and geopolitics in Central European states that acceded into the EU or NATO in 2004. The author examines assumptions that shaped these debates and influenced policy-making, combining fresh theoretical approaches from international relations and political geography with rich empirical material from Central Europe. This book provides the first in-depth analysis of security discourse in the region.



2.

Record Nr.

UNINA9910143740103321

Titolo

Genetics of autoimmunity [[electronic resource] /] / [editors: Gregory Bock and Jamie Goode]

Pubbl/distr/stampa

Chichester, UK ; ; Hoboken, NJ, USA, : Wiley, 2005

ISBN

1-280-23841-0

9786610238415

0-470-02139-X

0-470-02138-1

Descrizione fisica

1 online resource (261 p.)

Collana

Novartis Foundation symposium ; ; 267

Altri autori (Persone)

BockGregory

GoodeJamie

Disciplina

616.0796

616.978

Soggetti

Autoimmunity

Autoimmunity - Genetic aspects

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

"Symposium on Genomics of Autoimmunity, held at the Novartis Foundation, London, 22-24 June 2004."

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

GENETICS OF AUTOIMMUNITY; Contents; Participants; Chair's introduction; Patterns of genetic variation in humans and mice; Discussion; Haplotype tagging in pharmacogenetics; Discussion; Multiple sclerosis: a haplotype association study; Discussion; Mapping genes for asthma and psoriasis; Discussion; Natural genetic variants influencing type 1 diabetes in humans and in the NOD mouse; Discussion; The importance of epistatic interactions in the development of autoimmunity; Discussion; Mapping autoimmune disease genes in humans: lessons from IBD and SLE; Discussion

A combined genetics and genomics approach to unravelling molecular pathways in coeliac diseaseDiscussion; Progress towards understanding the genetic pathogenesis of systemic lupus erythematosus; Discussion; A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling; Discussion; Genetic lesions in thymic T cell clonal deletion and thresholds for autoimmunity; Discussion; An



autoimmune disease-associated CTLA4 splice variant lacking the B7 binding domain signals negatively in T cells; Discussion; Large-scale screens for cDNAs with in vivo activity; Discussion

Genomic mining of new genes and pathways in innate and adaptive immunityDiscussion; Index of contributors; Subject index

Sommario/riassunto

This title provides an extremely helpful analysis of genes that may be associated with autoimmunity, and answers questions such as how these genes can be identified, and how the functions of the gene products can be elucidated.Incorporating data on disease-associated chromosomal loci that has been accumulated from inbred mice, the title:* describes how some susceptibility loci may be common to many diseases, whereas others are relatively disease specific* discusses the importance of developing criteria for establishing the significance of these different categories of disease-as