1.

Record Nr.

UNINA9910451226403321

Titolo

The [Beta][subscript]3-adrenoreceptor / / edited by A. Donny Strosberg

Pubbl/distr/stampa

London ; ; New York : , : Taylor & Francis, , 2000

ISBN

0-429-16231-6

1-4822-2103-9

1-280-05226-0

0-585-46503-7

9786610052264

0-203-48444-4

Descrizione fisica

1 online resource (189 p.)

Collana

Taylor & Francis series in pharmaceutical sciences

Altri autori (Persone)

StrosbergA. D

Disciplina

612/.01575

Soggetti

Beta adrenoceptors

Adrenergic beta agonists

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references (p. 125-166) and index.

Nota di contenuto

Book Cover; Title; Contents; List of figures; List of tables; Contributors; Preface; Abbreviations used in this book; Structure and Function of the 3-Adrenoreceptor; Regulation of the 3-Adrenoreceptor Signalling Efficacy; Using Transgenic and Gene Knockout Techniques to Assess 3-Adrenoreceptor Function; 3-Adrenoreceptor Ligands and the Pharmacology of the 3-Adrenoreceptor; The Native Human 3-Adrenoreceptor; 3-Adrenoreceptor-Mediated Responses in Heart and Vessels; 3-Adrenoreceptors in Brown and White Adipocytes: Roles in Thermogenesis and Energy Balance

The Putative '4'-Adrenoreceptor and Other Atypical -AdrenoreceptorsReferences; Index

Sommario/riassunto

The Beta-3 Adrenoreceptor plays an important role in regulating human fat storage and variants of this receptor are thought to be relevant to diabetes.In addition to the major interest in obesity and diabetes expressed by the pharmaceutical industry, increasing numbers of academic groups are attracted by this general research area. This



renewed interest is of course in part stimulated by available financing from industry. It also reflects the growing realisation that metabolism remains an open frontier: little is known about adipocyte sub-populations, specific markers, or endocrine functio