1.

Record Nr.

UNINA9910450884203321

Autore

Danson Edwin <1948->

Titolo

Weighing the world [[electronic resource] ] : the quest to measure the Earth / / Edwin Danson

Pubbl/distr/stampa

Oxford ; ; New York, N.Y., : Oxford University Press, 2006

ISBN

0-19-029281-4

0-19-972509-8

1-280-84548-1

0-19-804013-X

Descrizione fisica

1 online resource (302 p.)

Disciplina

526/.1

Soggetti

Science - Europe - History - 18th century

Industrial revolution - Europe - History

Electronic books.

Earth Figure Measurement

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references (p. 277-282) and index.

Nota di contenuto

Contents; 1 I Cannot Be Wrong; 2 The Titan King; 3 A Calm and Gentle Character; 4 The Galileo of France; 5 Extreme Science; 6 Robberies and Depredations; 7 A Magnificent Military Sketch; 8 Persons Well Versed; 9 Very Expert in His Business; 10 A Passage with My Horse; 11 Frankenstein and Other Experiments; 12 A Remarkable Hill; 13 Important Observations; 14 So Great a Noise; 15 The Attraction of Mountains; 16 The Best of the Position; 17 Distinguished Merit; 18 Late by a Whole Year; 19 Geodetic Experiments; 20 I Know It Will Answer; 21 Offering Violence to Nature; 22 A Meritorious Foreigner

23 Men Worthy of Confidence24 Irregularities We Have Discovered; Appendix: Explanations and Definitions; Notes; Bibliography; Index

Sommario/riassunto

Preface. 1. I Cannot Be Wrong. 2. The Titan King. 3. A Calm And Gentle Character. 4. The Galileo Of France. 5. Extreme Science. 6. Robberies And Depredations. 7. A Magnificent Military Sketch. 8. Persons Well Versed. 9. Very Expert In His Business. 10. A Passage With My Horse. 11. Frankenstein And Other Experiments. 12. A Remarkable Hill. 13. Important Observations. 14. So Great A Noise. 15. The Attraction of



Mountains. 16. The Best Of The Position. 17. Distinguished Merit. 18. Late A Whole Year. 19. Geodetic Experiments. 20. I Know It Will Answer. 21. Offering Violence To Nature. 22. A Merito

2.

Record Nr.

UNINA9910298279703321

Titolo

Sugar Chains : Decoding the Functions of Glycans / / edited by Tadashi Suzuki, Kazuaki Ohtsubo, Naoyuki Taniguchi

Pubbl/distr/stampa

Tokyo : , : Springer Japan : , : Imprint : Springer, , 2015

ISBN

4-431-55381-9

Edizione

[1st ed. 2015.]

Descrizione fisica

1 online resource (295 p.)

Disciplina

570

572

614.5999

616079

Soggetti

Biochemistry

Cancer - Research

Immunology

Biochemistry, general

Cancer Research

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

1 N-Glycans and Quality Control of Proteins -- 2 Glycan-Mediated Protein Transport from the Endoplasmic Reticulum -- 3 Gangliosides and T-Cell Immunity -- 4 Gangliosides Regulate Tumor Properties: With Focus on the Suppression of Metastasis-Associated ppGalNAc-T13 with GM1 -- 5 Role of Glycans in Viral Infection -- 6 Discovery and Applications of a Novel Human Pluripotent Stem Cell-Specific Lectin Probe rBC2LCN -- 7 Glycan Structure and Neural Plasticity -- 8 The Involvement of Midkine, a Heparin-Binding Growth Factor, in Cancer Development -- 9 Tumor-Associated Glycans and Their Functional Roles in the Multistep Process of Human Cancer Progression -- 10 Mammalian Sialidase and Tumor Development -- 11 Roles of Glycans



in Immune Evasion from NK Immunity -- 12 Glycomic Analysis of Cancer -- 13 Glyco-Predisposing Factor of Diabetes -- 14 Macrophages Govern Ganglioside GM3 Expression in Adipocytes to Regulate Adipogenesis and Insulin Signaling in Homeostatic and Pathogenic Conditions -- 15 O-Mannosyl Glycan and Muscular Dystrophy -- 16 Glycans and Chronic Obstructive Pulmonary Disease (COPD) -- 17 α1,6-Fucosyltransferase Knockout Mice and Schizophrenia-Like Phenotype.  .

Sommario/riassunto

This book presents the latest breakthrough results in glycobiology regarding the roles of glycans in relation to quality control and transport of protein, the immune system, viral infection, stem cells, the neural system, and various diseases such as cancer, diabetes, chronic obstructive pulmonary disease, muscular dystrophy, and schizophrenia. Although glycoscience has long been regarded as a very specialized field with no simple analytical method, the recent explosive progress in research continues to provide limitless evidence that glycan chains are the key component in various biological phenomena. Cell surface glycans, for example, change with developmental stages or environmental conditions and thus represent a “face” of the cell that is utilized for identification of iPS and ES cells and as biomarkers in diagnosis or detection of cancer. This book comprises 17 chapters, each of which poses outstanding “glyco-related” questions enabling non-specialists to have a clearer idea about what the future direction for further investigation of glycans in their own research fields will be. Also including basic information to understand the nature of glycans, this title serves as an excellent “textbook” for researchers in diverse research fields who are not familiar with, but nevertheless interested in, glycan chains or sugar chains.