1.

Record Nr.

UNINA9910449862503321

Titolo

Novel compounds from natural products in the new millennium [[electronic resource] ] : potential and challenges / / editors, Benny K-H Tan, Boon-Huat Bay, Yi-Zhun Zhu

Pubbl/distr/stampa

Hackensack, N.J. ; ; Hong Kong, : World Scientific, c2004

ISBN

1-281-34759-0

9786611347598

981-256-221-4

Descrizione fisica

1 online resource (337 p.)

Altri autori (Persone)

TanBenny K-H

BayBoon-Huat

ZhuYi-Zhun

Disciplina

547.7

660.6

Soggetti

Natural products

Natural products - Therapeutic use

Pharmacognosy

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Contents               ; Foreword (by John Wong)                              ; Foreword (by Kurt Hostettmann)                                     ; Preface              ; 1. Plants in Drug Discovery-Creating a New Vision                                                        ; INTRODUCTION                   ; NATURAL PRODUCTS IN DRUG DISCOVERY - THE FUTURE                                                      ; ACCESS TO THE BIOME

ACQUISITION AND ANALYSIS OF TRADITIONAL KNOWLEDGE AND ON-GOING RESEARCH                                                                              BIOTECHNOLOGY DEVELOPMENT                                ; SAFETY AND EFFICACY OF PLANT MEDICINAL AGENTS                                                    ; DEREPLICATION STUDJES                            ; NATURAL PRODUCT STRUCTURE DIVERSIFICATION                                                ; CREATING A NEW VISION                            ; CHALLENGES FOR THE FUTURE                                ; CONCLUSION


REFERENCES                 2. The Bio-Extraction Industry in Jamaica: Potential and Challenges                                                                          ; INTRODUCTION                   ; REFERENCES                 ; 3. Structural Studies of Drug Metabolising Enzymes and the Relevance to Natural Product Development                                                                                                          ; INTRODUCTION                   ; THE IMPORTANCE OF DRUG METABOLISM IN DRUG DEVELOPMENT

CYTOCHROME P450 (CYP) ENZYMES                                    ARYLAMINE N-ACETYLTRANSFERASE (NAT)                                          ; CONCLUSION                 ; ACKNOWLEDGEMENT                      ; REFERENCES                 ; 4. Bioinformatics-Species Diversity Databases: Tools for Facilitating Natural Product Research                                                                                                     ; INTRODUCTION                   ; WHAT IS BIOINFORMATICS?                              ; WHAT ARE THE SUB-DISCIPLINES?

DATA-CENTERED VIEW                         TECHNOLOGY-CENTERED VIEW                               ; WHAT UNIFYING FRAMEWORKS CAN BE FOUND FOR BIOLOGICAL DATASETS?                                                                     ; CONCLUSION                 ; REFERENCES                 ; 5. From Genomes to Drugs with Bioinformatics                                                   ; INTRODUCTION                   ; SEQUENCE ANALYSIS                        ; SEQUENCE COMPARISON                          ; FINDING PARTICULAR SEQUENCE PATTERNS

PROTEIN STRUCTURE PREDICTION

Sommario/riassunto

There is continuing interest in natural products as sources of potentially new and exciting chemical compounds. This book brings together the knowledge, perspectives and research findings of a varied group of scientists on a wide range of topics, from microarrays, genetics and bioinformatics to yeast-based technologies and enzyme studies. Scientists and clinicians in life science research will find useful information on new research techniques and tools. For the agriculturist, there is interesting information on the potential and problems of natural-based pesticides. The cancer researcher will