1.

Record Nr.

UNINA9910446344103321

Titolo

Parasitic flatworms : molecular biology, biochemistry, immunology and physiology / / edited by Aaron G. Maule and Nikki J. Marks

Pubbl/distr/stampa

Wallingford, UK ; ; Cambridge, MA, : CABI, c2006

ISBN

1-280-73550-3

9786610735501

1-84593-039-8

Edizione

[1st ed.]

Descrizione fisica

1 online resource (468 p.)

Altri autori (Persone)

MauleAaron G

MarksNikki J

Disciplina

616.9/62

Soggetti

Platyhelminthes

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

The evolution of parasitism in flatworms / D.T.J. Littlewood -- Genomes and genomics of parasitic flatworms / D.A. Johnston -- Genetic discrimination of echinococcus species and strains / D.P. McManus -- Ribosomal DNA variation in parasitic flatworms / D. Blair -- Genetic studies on monogeneans with emphasis on Gyrodactylus / C.O. Cunningham and I. Matejusova -- The schistosome transcriptome / S. Verjovski-Almeida and R. DeMarco -- Transgenic flatworms / C.G. Grevelding -- Immunobiology of schistosomes / S.G. Forrester and E.J. Pearce -- Cestode infection : immunological considerations from host and tapeworm perspectives / D.M. McKay and R.A. Webb -- Signal transduction at the host-parasite interface / T.P. Yoshino, J.J. Vermeire and J.E. Humphries --

Parasite effects on the snail host transcriptome / M. Knight and N. Raghavan -- Developments in the chemotherapy of parasitic flatworms / G.C. Coles -- Drug resistance in schistosomes / T.A. Day and S. Botros -- Praziquantel : mechanism of action / R.M. Greenberg -- Cestode vaccine development / M.W. Lightowlers -- The development of a schistosome vaccine / R.A. Wilson and P.S. Coulson -- Flatworm parasite proteomics / R.M. Morphew, J. Barrett and P.M. Brophy -- Proteases in trematode biology / J.P. Dalton, C.R. Caffrey, M. Sajid, C. Stack, S. Donnelly, A. Loukas, T. Don, J. McKerrow, D.W. Halton and P.J.



Brindley -- Signalling molecules and nerve-muscle function / A.G. Maule, N.J. Marks and T.A. Day -- Unusual aspects of metabolism in flatworm parasites / A.G.M. Tielens and J.J. van Hellemond -- Glycoconjugate structures / M. Wuhrer and R. Geyer -- Gene silencing in flatworms using RNA interference / P.J. Skelly.

Sommario/riassunto

This book examines recent research into the molecular biology, genomics and transcriptomics of, and novel control strategies for, flatworm parasites. These include Cestodes (tapeworms) and Trematodes (flukes, schistosomes etc), which are the cause of a number of diseases of medical and veterinary importance. The book explores three main areas: phylogeny, genetics and transcriptomes; immunobiology, host-parasite interaction and control; and protein function, metabolism and physiology. Where appropriate, comparisons are made between different parasitic flatworms and between parasitic and free-li