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1. |
Record Nr. |
UNINA9910585998003321 |
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Autore |
Förster Stine von |
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Titolo |
Verbrechen gegen die Menschlichkeit durch Migrationskontrolle? : Eine völkerstrafrechtliche Untersuchung zur Situation an den südlichen EU-Außengrenzen |
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Pubbl/distr/stampa |
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Hamburg, : Hamburg University Press, 2019 |
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Descrizione fisica |
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1 electronic resource (382 p.) |
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Altri autori (Persone) |
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Soggetti |
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International criminal law |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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In her work, Stine von Förster examines the actions of state forces in migration control in Spain, Italy, Greece and Bulgaria. The focus is on the relevance under international criminal law of the handling of migrants in direct connection with irregular entry into the European Union. When examining the events at the borders of the southern EU member states, incidents on the Mediterranean Sea - i.e. before the actual border crossing - as well as the handling of irregular migrants directly following the border crossing are also taken into account. The main subject of the study is the question of whether the handling of irregular migrants at the southern external borders of the EU results in crimes against humanity as defined in Article 7 of the Rome Statute of the International Criminal Court by state forces. |
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2. |
Record Nr. |
UNINA9910438129503321 |
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Titolo |
Autophagy and cancer / / Hong-Gang Wang, editor |
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Pubbl/distr/stampa |
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New York, NY, : Springer, c2013 |
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ISBN |
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Edizione |
[1st ed. 2013.] |
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Descrizione fisica |
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1 online resource (261 p.) |
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Collana |
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Current cancer research ; ; 8 |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Carcinogenesis |
Cancer - Immunological aspects |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Nota di contenuto |
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Preface -- Historical Overview of Autophagy -- The Core Molecular Machinery of Autophagosome Formation -- The origin of autophagosomes: The beginning of an end -- Signal Transduction Regulation of Autophagy -- Role of Autophagy in Tumorigenesis -- Selective autophagy and cancer -- Oncogenes and tumor suppressor genes in autophagy -- Autophagy and Immunity -- Autophagy and the Tumor Microenvironment -- Autophagy and Cancer Therapy -- The Crosstalk between Apoptosis & Autophagy -- Autophagy and Cancer Drug Discovery -- Index. |
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Sommario/riassunto |
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This book covers the latest advances in the field of autophagy and cancer from the basics of the molecular machinery for autophagy induction and regulation up to current areas of interest, including modulation of autophagy and drug discovery for cancer prevention and treatment. The reader will be initially introduced to the historical context of autophagy, followed by a summary of the key players in autophagy, a discussion on the origin of autophagosomes, and an overview of signal transduction regulation of autophagy. The next chapters deal with the complex relationship between autophagy and tumorigenesis through in-depth discussions of how autophagy influences cell survival, apoptosis, inflammation, immunity, tumor microenvironment, metabolic stress, DNA damage, and genomic instability. The remaining chapters discuss how autophagy affects |
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cancer cell response to therapy and how to best modulate autophagy for therapeutic benefit - what to target and how to target. We hope that this monograph will be an invaluable reference source for professionals, students, postdoctoral fellows, and senior scientists working in the fields of autophagy and cancer. |
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