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1. |
Record Nr. |
UNINA9910438122103321 |
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Autore |
Mauri Roberto |
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Titolo |
Non-Equilibrium Thermodynamics in Multiphase Flows / / by Roberto Mauri |
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Pubbl/distr/stampa |
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Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 |
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ISBN |
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Edizione |
[1st ed. 2013.] |
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Descrizione fisica |
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1 online resource (271 p.) |
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Collana |
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Soft and Biological Matter, , 2213-1736 |
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Disciplina |
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Soggetti |
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Thermodynamics |
Chemistry, Physical and theoretical |
Amorphous substances |
Complex fluids |
Fluid mechanics |
Statistical physics |
Dynamics |
Polymers |
Physical Chemistry |
Soft and Granular Matter, Complex Fluids and Microfluidics |
Engineering Fluid Dynamics |
Complex Systems |
Polymer Sciences |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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From the Contents: Microscopic reversibility -- The Langevin equation -- The Fokker-Planck equation -- Stochastic differential calculus -- The path integral -- Balance equations -- The constitutive relations -- Multiphase Flows -- Effective constitutive relations -- Multiple scale analysis. |
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Sommario/riassunto |
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Non-equilibrium thermodynamics is a general framework that allows the macroscopic description of irreversible processes. This book introduces non-equilibrium thermodynamics and its applications to the rheology of multiphase flows. The subject is relevant to graduate students in chemical and mechanical engineering, physics and material |
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science. This book is divided into two parts. The first part presents the theory of non-equilibrium thermodynamics, reviewing its essential features and showing, when possible, some applications. The second part of this book deals with how the general theory can be applied to model multiphase flows and, in particular, how to determine their constitutive relations. Each chapter contains problems at the end, the solutions of which are given at the end of the book. No prior knowledge of statistical mechanics is required; the necessary prerequisites are elements of transport phenomena and on thermodynamics. “The style of the book is mathematical, but nonetheless it remains very readable and anchored in the physical world rather than becoming too abstract. Though it is up-to-date and includes recent important developments, there is a lot of classical material in the book, albeit presented with unprecedented clarity and coherence. The first six chapters are actually a very good introduction to the theory underlying many phenomena in soft matter physics, beyond the focus on flow and transport of the later chapters of the book.” Prof Richard A.L. Jones FRS, Pro-Vice-Chancellor for Research and Innovation, University of Sheffield. |
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2. |
Record Nr. |
UNINA9910557287703321 |
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Autore |
Cecchin Erika |
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Titolo |
Pharmacogenomics and Personalized Medicine |
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Pubbl/distr/stampa |
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Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
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Descrizione fisica |
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1 online resource (208 p.) |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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Pharmacogenomics is one of the emerging approaches to precision medicine, tailoring drug selection and dosing to the patient's genetic features. In recent years, several pharmacogenetic guidelines have been published by international scientific consortia, but the uptake in clinical practice is still poor. Many coordinated international efforts are ongoing in order to overcome the existing barriers to pharmacogenomic implementation. On the other hand, existing validated pharmacogenomic markers can explain only a minor part of the observed clinical variability in the therapeutic outcome. New investigational approaches are warranted, including a study of the pharmacogenomic role of the immune system genetics and of previously neglected rare genetic variants, reported to account for a large part of inter-individual variability in drug metabolism. In this book, we have collected a series of articles covering many aspects of pharmacogenomics. These include clinical implementation of pharmacogenomics in clinical practice, development of tools or infrastructures to support this process, research of new pharmacogenomics markers to increase drug efficacy and safety, and the impact of rare genetic variants in pharmacogenomics. |
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