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Record Nr. |
UNINA9910437848803321 |
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Titolo |
Mucosal immunology of acute bacterial pneumonia / / Alice Prince, editor |
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Pubbl/distr/stampa |
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New York, : Springer, 2013 |
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ISBN |
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1-283-93403-5 |
1-4614-5326-7 |
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Edizione |
[1st ed. 2013.] |
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Descrizione fisica |
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1 online resource (285 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Pneumonia - Immunological aspects |
Bacterial diseases - Immunological aspects |
Mucous membrane - Immunology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Alveolar macrophages – key coordinators of host defense -- Lung dendritic cells and pulmonary defense mechanisms against bacteria -- CD4 T cell immunity in the lung -- Neutrophil mediated defenses in bacterial pneumonia -- Toll-like receptors in the epithelium -- Type I IFN signaling in bacterial pneumonia -- Transcriptional signaling hubs in epithelial cells during pneumonia.- Innate immune responses in Ventilator Associated Pneumonia -- Streptococcus pneumoniae: The prototype of lung responses in pneumonia -- Staphylococcus aureus infection of the respiratory tract -- Pseudomonas aeruginosa: the consummate opportunistic pathogen of the lung. . |
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Sommario/riassunto |
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In contrast to the substantial literature that focuses upon innate immune signaling in the gut, there is remarkably less known about the response of the airway to bacterial pathogens. The purpose of this book will be to review the current status of theunderstanding of the pathogenesis of acute bacterial pneumonia, slanted toward the mucosal immunology of these infections. It will describe, in general, the signaling cascades that control the proinflammatory response to bacterial infection in the lung. How innate immune signaling is orchestrated in response to specific common airway pathogens is |
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