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Record Nr. |
UNINA9910437834303321 |
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Titolo |
Angiogenesis Modulations in Health and Disease : Practical Applications of Pro- and Anti-angiogenesis Targets / / edited by Shaker A. Mousa, Paul J. Davis |
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Pubbl/distr/stampa |
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Dordrecht : , : Springer Netherlands : , : Imprint : Springer, , 2013 |
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ISBN |
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Edizione |
[1st ed. 2013.] |
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Descrizione fisica |
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1 online resource (209 p.) |
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Disciplina |
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Soggetti |
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Medicine |
Neurosciences |
Pharmacy |
Life sciences |
Biotechnology |
Cell biology |
Biomedicine, general |
Life Sciences, general |
Cell Biology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Preface -- Angiogenesis assays: an appraisal of current techniques -- Survey of pro-angiogenesis strategies -- Angiogenesis modulation by arachidonic acid – derived lipids: positive and negative regulators of angiogenesis -- Pro-angiogenic activity of thyroid hormone analogues: Mechanisms, physiology and clinical prospects -- Actions of steroids and peptide hormones on angiogenesis -- Role of non-neuronal nicotinic acetylcholine receptors in angiogenesis modulation.- Catecholamine neurotransmitters: an angiogenic switch in the tumor microenvironment -- Impact of nanotechnology on therapeutic angiogenesis -- Survey of anti-angiogenesis strategies -- Tetraiodothyroacetic acid (tetrac), nanotetrac and anti-Angiogenesis -- Integrin antagonists and angiogenesis -- Anti-angiogenesis therapy as an adjunct to chemotherapy in oncology -- Anti-vegf strategies in ocular angiogenesis- mediated disorders, with special emphasis on |
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age-related macular degeneration -- Application of nanotechnology to targeting tumor angiogenesis for therapeutic benefit -- Biomarkers of response and resistance to anti-angiogenic treatment -- Speculations on new directions in which angiogenesis may proceed. Index. |
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Sommario/riassunto |
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This book is a major update of novel targets in angiogenesis modulation, including pro- and anti-angiogenesis. There is in-depth coverage of preclinical and clinical methods and models, investigational status, and clinical applications. The impact of nanotechnology in advancing the applications of pro-and anti-angiogenesis strategies is also highlighted, along with stem cell and biotechnologies in research and development of angiogenesis modulating targets. |
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