Zákon o {cCaron}TK : transformace na půli cesty Vývoj vztahů mezi politickou a mediální sférou v 90. letech 20. století / / Ludmila Truneckova

• Record Nr.: UNINA9910480611903321
• Autore: Trunečková Ludmila
• Pubbl/distr/stampa: Prague, Czech Republic : , : Karolinum, , 2015; ©2015
• ISBN: 80-246-3087-7
• Descrizione fisica: 1 online resource (157 pages)
• Disciplina: 070.435
• Soggetti: News agencies - Czech Republic - History - 20th century; Mass media - Political aspects - Czech Republic; Electronic books.
• Lingua di pubblicazione: Ceco
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Nota di bibliografia: Includes bibliographical references.

Electromagnetic modeling and simulation [[electronic resource] /] / Levent Sevgi

• Record Nr.: UNINA9910648493303321
• Autore: Sevgi Levent
• Pubbl/distr/stampa: Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2014]; [Piscataqay, New Jersey] : , : IEEE Xplore, , [2014]
• ISBN: 1-118-87711-X; 1-118-71644-2; 9781118716410
• Descrizione fisica: 1 online resource (666 pages)
• Collana: IEEE Press series on electromagnetic wave theory
• Classificazione: SCI022000
• Disciplina: 621.380285/53
• Soggetti: Electromagnetism - Computer simulation
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references at the end of each chapters and index.
• Nota di contenuto: Preface xvii -- About the Author xxvii -- Acknowledgments xxix -- 1 Introduction to MODSIM 1 -- 1.1 Models and Modeling, 2 -- 1.2 Validation, Verifi cation, and Calibration, 5 -- 1.3 Available Core Models, 7 -- 1.4 Model Selection Criteria, 9 -- 1.5 Graduate Level EM MODSIM Course, 11 -- 1.5.1 Course Description and Plan, 11 -- 1.5.2 Available Virtual EM Tools, 12 -- 1.6 EM-MODSIM Lecture Flow, 12 -- 1.7 Two Level EM Guided Wave Lecture, 17 -- 1.8 Conclusions, 19 -- References, 19 -- 2 Engineers Speak with Numbers 23 -- 2.1 Introduction, 23 -- 2.2 Measurement, Calculation, and Error Analysis, 24 -- 2.3 Significant Digits, Truncation, and Round-Off Errors, 27 -- 2.4 Error Propagation, 28 -- 2.5 Error and Confi dence Level, 29 -- 2.5.1 Predicting the Population's Confidence Interval, 33 -- 2.6 Hypothesis Testing, 36 -- 2.6.1 Testing Population Mean, 38 -- 2.6.2 Testing Population Proportion, 39 -- 2.6.3 Testing Two Population Averages, 39 -- 2.6.4 Testing Two Population Proportions, 39 -- 2.6.5 Testing Paired Data, 40 -- 2.7 Hypothetical Tests on Cell Phones, 41 -- 2.8 Conclusions, 45 -- References, 45 -- 3 Numerical Analysis in Electromagnetics 47 -- 3.1 Taylor's Expansion and Numerical Differentiation, 47 -- 3.1.1 Taylor's Expansion and Ordinary Differential Equations, 50 -- 3.1.2 Poisson and Laplace Equations, 52 ; -- 3.1.3 An Iterative (Finite-Difference) Solution, 53 -- 3.2 Numerical Integration, 58 -- 3.2.1 Rectangular Method, 58 -- 3.3 Nonlinear Equations and Root Search, 62 -- 3.4 Linear Systems of Equations, 64 -- References, 69 -- 4 Fourier Transform and Fourier Series 71 -- 4.1 Introduction, 71 -- 4.2 Fourier Transform, 72 -- 4.2.1 Fourier Transform (FT), 72 -- 4.2.2 Discrete Fourier Transform (DFT), 74 -- 4.2.3 Fast Fourier Transform (FFT), 76 -- 4.2.4 Aliasing, Spectral Leakage, and Scalloping Loss, 77 -- 4.2.5 Windowing and Window Functions, 80 -- 4.3 Basic Discretization Requirements, 81 -- 4.4 Fourier Series Representation, 85 -- 4.5 Rectangular Pulse and Its Harmonics, 92.; 4.6 Conclusions, 92 -- References, 94 -- 5 Stochastic Modeling in Electromagnetics 95 -- 5.1 Introduction, 95 -- 5.2 Radar Signal Environment, 98 -- 5.2.1 Random Number Generation, 98 -- 5.2.2 Noise Generation, 101 -- 5.2.3 Signal Generation, 108 -- 5.2.4 Clutter Generation, 108 -- 5.3 Total Radar Signal, 111 -- 5.4 Decision Making and Detection, 114 -- 5.4.1 Hypothesis Operating Characteristics (HOCs), 115 -- 5.4.2 A Communication/Radar Receiver, 119 -- 5.5 Conclusions, 129 -- References, 130 -- 6 Electromagnetic Theory: Basic Review 133 -- 6.1 Maxwell Equations and Reduction, 133 -- 6.2 Waveguiding Structures, 134 -- 6.3 Radiation Problems and Vector Potentials, 136 -- 6.4 The Delta Dirac Function, 138 -- 6.5 Coordinate Systems and Basic Operators, 139 -- 6.6 The Point Source Representation, 141 -- 6.7 Field Representation of a Point/Line Source, 142 -- 6.8 Alternative Field Representations, 143 -- 6.9 Transverse Electric/Magnetic Fields, 145 -- 6.9.1 The 3D TE/TM Waves, 145 -- 6.9.2 The 2D TE/TM Waves, 146 -- 6.10 The TE/TM Source Injection, 151 -- 6.11 Second-Order EM Differential Equations, 154 -- 6.12 EM Wave-Transmission Line Analogy, 155 -- 6.13 Time Dependence in Maxwell Equations, 157 -- 6.14 Physical Fundamentals, 158 -- References, 158 -- 7 Sturm-Liouville Equation: The Bridge between Eigenvalue and Green's Function Problems 161 -- 7.1 Introduction, 161 -- 7.2 Guided Wave Scenarios, 162 -- 7.3 The Sturm-Liouville Equation, 165 -- 7.3.1 The Eigenvalue Problem, 167 -- 7.3.2 The Green's Function (GF) Problem, 168 -- 7.3.3 Finite z-Domain Problem, 169 -- 7.3.4 Infi nite z-Domain Problem, 170 -- 7.3.5 Relation between Eigenvalue and Green's Function Problems, 171 -- 7.4 Conclusions, 172 -- References, 173 -- 8 The 2D Nonpenetrable Parallel Plate Waveguide 175 -- 8.1 Introduction, 176 -- 8.2 Propagation Inside a 2D-PEC Parallel Plate Waveguide, 177 -- 8.2.1 Formulation of the TE- and TM-Type Problems, 178 -- 8.2.2 The Green's Function Problem, 181 -- 8.2.3 Accessing the Spectral Domain: Separation of Variables, 182.; 8.2.4 Spectral Representations: Eigenvalue Problems, 183 -- 8.2.5 Spectral Representations: 1D Characteristic Green's Functions, 184 -- 8.2.6 The 2D Green's Function Problem: Alternative Representations, 185 -- 8.3 Alternative Representation: Eigenray Solution, 187 -- 8.3.1 Relation between Eigenmode and Eigenray Representations, 191 -- 8.3.2 2D GF and Hybrid Ray-Mode Decomposition, 192 -- 8.4 A 2D-PEC Parallel Plate Waveguide Simulator, 194 -- 8.4.1 Representations Used for Mode, Ray, and Hybrid Solutions, 195 -- 8.4.2 MATLAB Packages: RayMode and Hybrid, 207 -- 8.4.3 Numerical Examples, 210 -- 8.5 Eigenvalue Extraction from Propagation Characteristics, 215 -- 8.5.1 Longitudinal Correlation Function, 215 -- 8.5.2 Numerical Illustrations, 217 -- 8.6 Tilted Beam Excitation, 221 -- 8.7 Conclusions, 223 -- References, 225 -- 9 Wedge Waveguide with Nonpenetrable Boundaries 227 -- 9.1 Introduction, 228 -- 9.2 Statement of the Problem: Physical Configuration and Ray-Asymptotic ; Guided Wave Schematizations, 229 -- 9.3 Source-Free Solutions, 230 -- 9.3.1 Separable Coordinates: Conventional NM, 230 -- 9.3.2 Weakly Nonseparable Coordinates: AM, 231 -- 9.3.3 Uniformizing the AM Near Caustics: IM, 232 -- 9.4 Test Problem: The 2D Line-Source-Excited Nonpenetrable Wedge Waveguide, 234 -- 9.4.1 Exact Solution in Cylindrical Coordinate, 234 -- 9.4.2 Approximate Solutions in Rectangular Coordinates, 241 -- 9.4.3 IM Spectral Representation, 244 -- 9.5 The MATLAB Package “WedgeGUIDE,” 247 -- 9.6 Numerical Tests and Illustrations, 249 -- 9.7 Conclusions, 256 -- Appendix 9A: Formation of the Spectral IM Integral in Section 9.3.3, 257 -- References, 262 -- 10 High Frequency Asymptotics: The 2D Wedge Diffraction Problem 265 -- 10.1 Introduction, 266 -- 10.2 Plane Wave Illumination and HFA Models, 268 -- 10.2.1 Exact Solution by Series Summation, 268 -- 10.2.2 The Physical Optics (PO) Solution, 270 -- 10.2.3 The PTD Solution, 272 -- 10.2.4 The UTD Solution, 273 -- 10.2.5 The Parabolic Equation (PE) Solution, 275.; 10.3 HFA Models under Line Source (LS) Excitations, 275 -- 10.3.1 Exact Solution by Series Summation, 276 -- 10.3.2 Exact Solution by Integral, 277 -- 10.3.3 The Parabolic Equation (PE) Solution, 277 -- 10.4 Basic MATLAB Scripts, 278 -- 10.5 The WedgeGUI Virtual Tool and Some Examples, 291 -- 10.6 Conclusions, 297 -- References, 298 -- 11 Antennas: Isotropic Radiators and Beam Forming/Beam Steering 301 -- 11.1 Introduction, 301 -- 11.2 Arrays of Isotropic Radiators, 303 -- 11.3 The ARRAY Package, 306 -- 11.4 Beam Forming/Steering Examples, 310 -- 11.5 Conclusions, 317 -- References, 318 -- 12 Simple Propagation Models and Ray Solutions 319 -- 12.1 Introduction, 320 -- 12.2 Ray-Tracing Approaches, 321 -- 12.3 A Ray-Shooting MATLAB Package, 323 -- 12.4 Characteristic Examples, 329 -- 12.5 Flat-Earth Problem and 2Ray Model, 333 -- 12.6 Knife-Edge Problem and 4Ray Model, 338 -- 12.7 Ray Plus Diffraction Models, 348 -- 12.8 Conclusions, 351 -- References, 351 -- 13 Method of Moments 353 -- 13.1 Introduction, 353 -- 13.2 Approximating a Periodic Function by Other Functions: Fourier Series Representation, 354 -- 13.3 Introduction to the MoM, 359 -- 13.4 Simple Applications of MoM, 361 -- 13.4.1 An Ordinary Differential Equation, 361 -- 13.4.2 The Parallel Plate Capacitor, 364 -- 13.4.3 Propagation over PEC Flat Earth, 366 -- 13.5 MoM Applied to Radiation and Scattering Problems, 372 -- 13.5.1 A Complex Antenna Structure, 372 -- 13.5.2 Ground Wave Propagation Modeling, 373 -- 13.5.3 EM Scattering from Infinitely Long Cylinder, 376 -- 13.5.4 3D RCS Modeling, 381 -- 13.6 MoM Applied to Wedge Diffraction Problem, 386 -- 13.7 MoM Applied to Wedge Waveguide Problem, 397 -- 13.8 Conclusions, 402 -- References, 402 -- 14 Finite-Difference Time-Domain Method 407 -- 14.1 FDTD Representation of EM Plane Waves, 407 -- 14.1.1 Maxwell Equations and Plane Waves, 408 -- 14.1.2 FDTD and Discretization, 410 -- 14.1.3 A One-Dimensional FDTD MATLAB Script, 417 -- 14.1.4 MATLAB-Based FDTD1D Package, 417.; 14.2 Transmission Lines and Time-Domain Reflectometer, 429 -- 14.2.1 Transmission Line (TL) Theory, 430 -- 14.2.2 Plane Wave-Transmission Line Analogy, 434 -- 14.2.3 FDTD Representation of TL Equations, 437 -- 14.2.4 MATLAB-Based TDRMeter Package, 447 -- 14.2.5 Fourier Analysis and Reflection Characteristics, 454 -- 14.2.6 Laplace Analysis and Fault Identification, 456 -- 14.2.7 Step Response, 464 -- 14.3 1D FDTD with Second-Order Differential Equations, 468 -- 14.4 Two-Dimensional (2D) FDTD Modeling, 472 -- 14.4.1 Field Components and FDTD Equations, 476 -- 14.4.2 FDTD-Based Virtual Tool: MGL2D Package, 477 -- 14.4.3 Characteristic Examples, 479 -- 14.5 Canonical 2D Wedge Scattering Problem, 494 -- 14.5.1 Problem ; Postulation, 494 -- 14.5.2 Review of Analytical Models, 496 -- 14.5.3 The FDTD Model, 499 -- 14.5.4 Discretization and Dey-Mittra Approach, 502 -- 14.5.5 The WedgeFDTD Package and Examples, 505 -- 14.5.6 Wedge Diffraction and FDTD versus MoM, 510 -- 14.6 Conclusions, 512 -- References, 512 -- 15 Parabolic Equation Method 515 -- 15.1 Introduction, 516 -- 15.2 The Parabolic Equation (PE) Model, 518 -- 15.3 The Split-Step Parabolic Equation (SSPE) Propagation Tool, 520 -- 15.4 The Finite Element Method-Based PE Propagation Tool, 528 -- 15.5 Atmospheric Refractivity Effects, 531 -- 15.6 A 2D Surface Duct Scenario and Reference Solutions, 533 -- 15.7 LINPE Algorithm and Canonical Tests/Comparisons, 538 -- 15.8 The GrSSPE Package, 558 -- 15.9 The Single-Knife-Edge Problem, 566 -- 15.10 Accurate Source Modeling, 571 -- 15.11 Dielectric Slab Waveguide, 580 -- 15.11.1 Even and Odd Symmetric Solutions, 582 -- 15.11.2 The SSPE Propagator and Eigenvalue Extraction, 584 -- 15.11.3 The Matlab-Based DiSLAB Package, 585 -- 15.12 Conclusions, 591 -- References, 591 -- 16 Parallel Plate Waveguide Problem 595 -- 16.1 Introduction, 595 -- 16.2 Problem Postulation and Analytical Solutions: Revisited, 599 -- 16.2.1 Green's Function in Terms of Mode Summation, 602 -- 16.2.2 Mode Summation for a Tilted/Directive Antenna, 604.; 16.2.3 Eigenray Representation, 606 -- 16.2.4 Hybrid Ray + Image Method, 613 -- 16.3 Numerical Models, 613 -- 16.3.1 Split Step Parabolic Equation Model, 613 -- 16.3.2 Finite-Difference Time-Domain Model, 617 -- 16.3.3 Method of Moments (MoM), 622 -- 16.4 Conclusions, 638 -- References, 639 -- Appendix A Introduction to MATLAB 643 -- Appendix B Suggested References 653 -- Appendix C Suggested Tutorials and Feature Articles 655 -- Index 659.
• Sommario/riassunto: "Electromagnetic modeling is essential to the design and modeling of antenna, radar, satellite, medical imaging, and other applications. In Electromagnetic Modeling and Simulation, author Levent Sevgi explains techniques for solving real-time complex physical problems using MATLAB-based short scripts and comprehensive virtual tools. The book thoroughly covers the physics, mathematical background, analytical solutions, and code development of electromagnetic modeling. Access to online MATLAB scripts and coding tools render this book an ideal resource for electrical engineers and researchers"--; "Provides the reader with first steps in EM MODSIM as well as tools for medium and high-level code developers and users"--

MHC class I antigens in malignant cells : immune escape and response to immunotherapy / / Natalia Aptsiauri, Angel Miguel Garcia-Lora, Teresa Cabrera

• Record Nr.: UNINA9910437613903321
• Autore: Aptsiauri Natalia
• Pubbl/distr/stampa: New York, : Springer, c2013
• ISBN: 1-4614-6543-5
• Edizione: [1st ed. 2013.]
• Descrizione fisica: 1 online resource (51 p.)
• Collana: SpringerBriefs in cancer research ; ; 6
• Altri autori (Persone): Garcia-LoraAngel Miguel; CabreraTeresa
• Disciplina: 616.99/4079
• Soggetti: Oncology; Immunology
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di contenuto: Overview of MHC Class I Antigens -- HLA Class I Expression In Human Cancer -- MHC Class I Expression In Experimental Mouse Models Of Cancer: Immunotherapy Of Tumors With Different MHC-I Expression Patterns -- Potential Therapeutic Approaches For Increasing Tumor Immunogenicity By Upregulation Of Tumor HLA Class I Expression -- Conclusion.
• Sommario/riassunto: Abnormal expression of MHC class I molecules in malignant cells is a frequent occurrence that ranges from total loss of all class I antigens to partial loss of MHC specific haplotypes or alleles. Different mechanisms are described to be responsible for these alterations, requiring different therapeutic approaches. A complete characterization of these molecular defects is important for improvement of the strategies for the selection and follow-up of patients undergoing T-cell based cancer immunotherapy. Precise identification of the mechanism leading to MHC class I defects will help to develop new personalized patient-tailored treatment protocols. There is significant new research on the prevalence of various patterns of MHC class I defects and the underlying molecular mechanisms in different types of cancer. In contrast, few data is available on the changes in MHC class I expression during the course of cancer immunotherapy, but the authors have recently made discoveries that show the progression or regression of a ; tumor lesion in cancer patients undergoing immunotherapy depends on the molecular mechanism responsible for the MHC class I alteration and not on the type of immunotherapy used. According to this notion, the nature of the preexisting MHC class I lesion in the cancer cell has a crucial impact on determining the final outcome of cancer immunotherapy. This SpringerBrief will present how MHC class 1 is expressed, explain its role in tumor progression, and its role in resistance to immunotherapy. .