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1. |
Record Nr. |
UNINA9910455104303321 |
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Autore |
Goldstein David B |
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Titolo |
Jacob's legacy [[electronic resource] ] : a genetic view of Jewish history / / David B. Goldstein |
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Pubbl/distr/stampa |
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New Haven, : Yale University Press, c2008 |
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ISBN |
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1-282-08941-2 |
9786612089411 |
0-300-14510-1 |
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Descrizione fisica |
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1 online resource (176 p.) |
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Disciplina |
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Soggetti |
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Jews - History |
Jews - Origin |
Human genetics |
Jews - ethnology |
Jews - Genetics |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Bibliographic Level Mode of Issuance: Monograph |
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Nota di bibliografia |
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Includes bibliographical references (p. 129-139) and index. |
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Nota di contenuto |
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Keeping God's house : Y chromosomes and Old Testament priests -- Lost tribe no more? The Black Jews of South Africa -- Looking out for number two : the case of the Ashkenazi Levites -- Those Jewish mothers : the development of female-defined ethnicity in the Jewish diaspora -- Look on mine affliction : genetic diseases and Jewish history -- Jews, genes, and the future. |
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Sommario/riassunto |
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Who are the Jews? Where did they come from? What is the connection between an ancient Jewish priest in Jerusalem and today's Israeli sunbather on the beaches of Tel Aviv? These questions stand at the heart of this engaging book. Geneticist David Goldstein analyzes modern DNA studies of Jewish populations and examines the intersections of these scientific findings with the history (both biblical and modern) and oral tradition of the Jews. With a special gift for translating complex scientific concepts into language understandable to all, Goldstein delivers an accessible, personal, and fascinating book that tells the history of a group of people through the lens of genetics. |
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In a series of detective-style stories, Goldstein explores the priestly lineage of Jewish males as manifested by Y chromosomes; the Jewish lineage claims of the Lemba, an obscure black South African tribe; the differences in maternal and paternal genetic heritage among Jewish populations; and much more. The author also grapples with the medical and ethical implications of our rapidly growing command of the human genomic landscape. The study of genetics has not only changed the study of Jewish history, Goldstein shows, it has altered notions of Jewish identity and even our understanding of what makes a people a people. |
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2. |
Record Nr. |
UNINA9910437612203321 |
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Titolo |
Mechanisms and Emerging Therapies in Tremor Disorders / / edited by Giuliana Grimaldi, Mario Manto |
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Pubbl/distr/stampa |
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New York, NY : , : Springer New York : , : Imprint : Springer, , 2013 |
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ISBN |
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1-283-62363-3 |
9786613936080 |
1-4614-4027-0 |
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Edizione |
[1st ed. 2013.] |
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Descrizione fisica |
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1 online resource (489 p.) |
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Collana |
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Contemporary Clinical Neuroscience, , 2627-5341 |
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Altri autori (Persone) |
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GrimaldiGiuliana |
MantoMario |
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Disciplina |
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Soggetti |
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Medicine - Research |
Biology - Research |
Neurology |
Biomedical Research |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Part 1: Fundamental aspects -- Definition of tremor -- Membrane mechanisms of tremor -- Rodent models of tremor -- Advances in genetics of human tremor -- Musculo-skeletal models of tremor -- Part 2: The various forms of tremor in clinical practice: presentation |
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and mechanism -- Physiological tremor -- Rest tremor -- Postural tremors -- Isometric tremor -- Essential Tremor and Other Forms of Kinetic Tremor -- Dystonic tremor -- Orthostatic tremor -- Vocal tremor -- Update in Familial Cortical Myoclonic tremor with Epilepsy (FCMTE) -- Post-traumatic tremor and Other Post-Traumatic Movement Disorders -- Psychogenic tremor -- Tremor in childhood -- Part 3: Assessment of tremor: clinical, neurophysiological and neuroimaging aspects -- Assessment of tremor: clinical and functional scales -- Instrumentation: classical and emerging techniques -- Signal processing -- Diffusion imaging in tremor -- The metabolic networks in Parkinson's disease -- Part 4: Therapies of tremor -- Pharmacological treatments of tremor -- Thalamotomy -- Brain Stimulation -- Dopaminergic Influences on Rest and Action Tremors and Emerging Therapies for Tremor. |
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Sommario/riassunto |
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Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex up to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness and damping are all factors influencing features of tremor. This book discusses the pathophysiology of tremor including membrane mechanisms and rodent models, the advances in genetics and the musculoskeletal models pertinent to body oscillations. The main forms of tremor encountered during clinical practice are considered, taking into account neuroimaging aspects. The book covers recent advances in methodologies and techniques of assessment, and provides practical informations for the daily management. In addition to pharmacological treatments, neurosurgical approaches such as deep brain stimulation (DBS) and thalamotomy are discussed. Emerging techniques under development are also introduced. Future challenges are also presented. |
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