1.

Record Nr.

UNINA9910437610303321

Autore

Muley Vijaykumar Yogesh

Titolo

Genome-wide prediction and analysis of protein-protein functional linkages in bacteria / / Vijaykumar Yogesh Muley, Vishal Acharya

Pubbl/distr/stampa

New York, NY, : Springer, 2012, c2013

ISBN

1-4614-4705-4

Edizione

[1st ed. 2013.]

Descrizione fisica

1 online resource (65 p.)

Collana

SpringerBriefs in systems biology, , 2193-4746

Altri autori (Persone)

AcharyaVishal

Disciplina

572.86

Soggetti

Functional genomics

Protein-protein interactions

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references.

Nota di contenuto

Introduction -- From genomes to protein functions -- Co-evolutionary signals within genome sequences reflect functional dependence of proteins -- Chromosomal proximity of genes as an indicator of functional linkage -- Analyses of complex genome-scale biological networks -- Applications of protein interaction networks.

Sommario/riassunto

Using genome sequencing, one can predict possible interactions among proteins. There are very few titles that focus on protein-protein interaction predictions in bacteria. The authors will describe these methods and further highlight its use to predict various biological pathways and complexity of the cellular response to various environmental conditions. Topics include analysis of complex genome-scale protein-protein interaction networks, effects of reference genome selection on prediction accuracy, and genome sequence templates to predict protein function.