1.

Record Nr.

UNINA9910411946003321

Titolo

Cardiovascular Calcification and Bone Mineralization / / edited by Elena Aikawa, Joshua D. Hutcheson

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Humana, , 2020

ISBN

3-030-46725-2

Edizione

[1st ed. 2020.]

Descrizione fisica

1 online resource (XXI, 563 p. 108 illus., 102 illus. in color.)

Collana

Contemporary Cardiology, , 2196-8969

Disciplina

616.1

Soggetti

Cardiology

Pathology

Biomedical engineering

Biomedical Engineering/Biotechnology

Calcificació

Biomineralització

Malalties del cor

Malalties dels ossos

Cardiologia

Llibres electrònics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Part I. Cardiovascular Calcification -- Chapter 1. Pathology of Arterial and Valvular Calcification -- Chapter 2. Developmental Pathways in Cardiovascular Calcification -- Chapter 3. Differential Mechanisms of Arterial and Valvular Calcification -- Chapter 4. Calcification in Aortic Valve Replacement -- Chapter 5. Role of Extracellular Vesicles in Cardiovascular Calcification -- Chapter 6. Biomechanics, Mechanobiology, and Cardiovascular Calcification -- Chapter 7. Cardiovascular Calcification in Diabetics -- Chapter 8. Cardiovascular Calcification in Chronic Kidney Disease -- Chapter 9. Cardiovascular Calcification in Peripheral Artery Disease -- Chapter 10. Cardiovascular Calcification in Pediatrics and Progeria -- Chapter 11. Imaging of Early Calcification -- Chapter 12. Calcification Paradox – Bone vs Vascular Calcification -- Chapter 13. Clinical Trials in Cardiovascular



Calcification -- Part II. Ectopic Calcification -- Chapter 14. Calcification in the Brain -- Chapter 15. Calcification in the Kidney -- Chapter 16. Calcification in the Liver and Lungs -- Chapter 17. Placental Calcification in Newborns and its Clinical Implications -- Chapter 18. Breast Cancer Microcalcification -- Chapter 19. Calcification Following Traumatic Blast Injury -- Part III. Bone Mineralization -- Chapter 20. Extracellular Matrix and Mineralization in Skeletal Development -- Chapter 21. Cellular Contributors to Bone Homeostasis -- Chapter 22. Biomechanics and Mechanobiology in Bone Remodeling -- Chapter 23. Osteogenesis Imperfecta and Congenital Disorders -- Chapter 24. Therapeutic Strategies for Pathological Bone Remodeling.

Sommario/riassunto

The book covers the basic science and clinical aspects of cardiovascular calcification and bone mineralization. Cardiovascular calcification is the leading predictor of cardiovascular morbidity and mortality, with a predictive value more significant than blood lipid levels. The presence of calcific mineral in cardiovascular tissues alters biomechanical performance, increasing workload on the heart and potentiating atherosclerotic plaque rupture and subsequent heart attack and stroke. This book examines the role of calcification in cardiovascular disease covering topics such as calcification in the atherosclerotic plaques and aortic valves arteries and valves, aortic valve replacement, peripheral artery disease, imaging of early calcification and target discovery. In addition, various forms of ectopic calcification as well as mechanisms of bone mineralization are discussed. Cardiovascular Calcification and Bone Mineralization is an essential resource for clinicians, researchers, and other medical professionals in cardiology, pathology, and biomedical engineering.