1.

Record Nr.

UNINA9910410046703321

Autore

Lemmerer Miran

Titolo

Chemoselective Nucleophilic α-Amination of Amides / / by Miran Lemmerer

Pubbl/distr/stampa

Wiesbaden : , : Springer Fachmedien Wiesbaden : , : Imprint : Springer Spektrum, , 2020

ISBN

3-658-30020-5

Edizione

[1st ed. 2020.]

Descrizione fisica

1 online resource (68 pages)

Collana

BestMasters, , 2625-3615

Disciplina

547.042

Soggetti

Asymmetric synthesis

Chemical structure

Organic compounds - Synthesis

Chemistry

Asymmetric Synthesis

Structure And Bonding

Synthetic Chemistry Methodology

Reactive Precursor

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Traditional Umpolung Reactions in Organic Chemistry -- Insight into Electrophilic Amide Activation -- Results and Discussion of a New α-Amination Method via Umpolung of Amides -- α-Arylation of Carbonlys via a Smiles Rearrangement.

Sommario/riassunto

α-Amino carbonyl compounds are omnipresent in all living organisms, making their selective synthesis highly sought after. However, the synthesis of α-amino amides, a subclass of α-amino carbonyls, in the presence of other carbonyls is usually challenging, due to the required harsh conditions. Miran Lemmerer expands a novel chemoselective approach for the synthesis of these intriguing molecules together with Univ.-Prof. Dr. Nuno Maulide’s team. Contents Traditional Umpolung Reactions in Organic Chemistry Insight into Electrophilic Amide Activation Results and Discussion of a New α-Amination Method via Umpolung of Amides α-Arylation of Carbonlys via a Smiles Rearrangement Target Groups Scientists and students in the field of



organic chemistry, especially in methodology development The Author Miran Lemmerer is currently pursuing his PhD studies under supervision of Prof. Dr. Nuno Maulide at the Department of Organic Chemistry, University of Vienna, Austria. .