1.

Record Nr.

UNINA9910409701003321

Titolo

Tumor Microenvironment : Extracellular Matrix Components – Part A / / edited by Alexander Birbrair

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020

ISBN

3-030-40146-4

Edizione

[1st ed. 2020.]

Descrizione fisica

1 online resource (XI, 181 p. 29 illus., 24 illus. in color.)

Collana

Advances in Experimental Medicine and Biology, , 0065-2598 ; ; 1245

Disciplina

611.0182

Soggetti

Cancer research

Stem cells

Regenerative medicine

Tissue engineering

Cancer Research

Stem Cells

Regenerative Medicine/Tissue Engineering

Tumors

Càncer

Cèl·lules mare

Llibres electrònics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Includes index.

Nota di contenuto

The tumor microenvironment: focus on extracellular matrix -- Keratan Sulphate in the Tumour Environment -- Hyaluronan in the tumor microenvironment -- Fibronectin in the tumor microenvironment -- Matrix metalloproteinases role in tumor microenvironment -- Flipping the Molecular Switch: Influence of Perlecan and its Modifiers in the Tumor Microenvironment -- Heparan sulfate in the tumor microenvironment -- The role of Glypican-1 in the tumour microenvironment -- Index.

Sommario/riassunto

Revealing essential roles of the tumor microenvironment in cancer progression, this volume focuses on the extracellular matrix components with the tumor during cancer development. Further, it



teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include heparan sulphate, hyaluronan, fibronectin, perlecan, glypican, matrix metalloproteinases, and much more. Taken alongside its companion volumes, Tumor Microenvironment: Extracellular Matrix Components – Part A updates us on what we know about the different aspects of the tumor microenvironment, as well as apprises us on the future advances in the field. For the newer generation of researchers, this volume serves as a useful introduction to the history of scientists’ focus on the tumor microenvironment, and explores how this knowledge is currently applied in cancer treatments. The book will be an essential text for advanced cell biology and cancer biology students, as well as for scientists seeking an update on the developments in tumor microenvironment research. All of the chapter authors are renowned international experts in the field of cancer biology, and in the specific subfields that are the focus of their chapters.