1.

Record Nr.

UNINA9910702109803321

Titolo

Furthering Asbestos Claim Transparency (FACT) Act of 2012 [[electronic resource] ] : hearing before the Subcommittee on Courts, Commercial and Administrative Law of the Committee on the Judiciary, House of Representatives, One Hundred Twelfth Congress, second session, on H.R. 4369, May 10, 2012

Pubbl/distr/stampa

Washington : , : U.S. G.P.O., , 2012

Descrizione fisica

1 online resource (iv, 239 pages)

Soggetti

Asbestos - Law and legislation - United States

Products liability - Asbestos - United States

Toxic torts - United States

Actions and defenses - United States

Bankruptcy trustees - United States

Fraud - United States - Prevention

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Title from title screen (viewed on Oct. 5, 2012).

"Serial no. 112-120."

Nota di bibliografia

Includes bibliographical references.



2.

Record Nr.

UNINA9910409691303321

Titolo

Myosins : A Superfamily of Molecular Motors / / edited by Lynne M. Coluccio

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2020

ISBN

3-030-38062-9

Edizione

[2nd ed. 2020.]

Descrizione fisica

1 online resource (xi, 455 pages)

Collana

Advances in Experimental Medicine and Biology, , 0065-2598 ; ; 1239

Disciplina

572.6

Soggetti

Molecular biology

Proteins

Cytology

Molecular Medicine

Protein Science

Cell Biology

Protein Structure

Proteïnes

Estructura molecular

Citologia

Llibres electrònics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Introduction -- Myosin Structure -- Cargo Binding by Unconventional Myosins -- Cryo-EM of Actin-Myosin Structures -- Small Molecule Effectors of Myosin Function -- Single-Molecule Biophysical Techniques to Study Actomyosin Force Transduction -- High-Speed Atomic Force Microscopy to Study Myosin Motility -- How Myosin 5 Walks Deduced from Single-Molecule Biophysical Approaches -- How Actin Tracks Affect Myosin Motors -- Myosins in the Nucleus -- Myosins in Cytokinesis -- Myosins and Disease -- Myosins and Hearing -- The Actomyosin Systems in Apicomplexa -- Approaches to Identify and Characterise MYO6-Cargo Interactions -- Class IX Myosins: Motorized RhoGAP Signaling Molecules -- Myosin X -- Myosin XVI -- Myosin XVIII -- Myosin XIX.



Sommario/riassunto

Myosins are molecular motors that use the energy from ATP hydrolysis to move and exert tension on actin filaments. Although the best-known myosin is myosin II, which powers skeletal muscle contraction, there are at least two dozen classes of myosins, and cells generally express multiple isoforms. Myosins are involved in multiple cellular activities including cell structure, cell migration, intracellular trafficking, and cell-cell contact. Importantly, loss of function and mutation are associated with diseases including myopathies, hearing impairment, glomerulosclerosis, and cancer. Written by international experts in myosin motors and the approaches used to study them, this book is expected to provide a comprehensive assessment of the current status of our understanding of the structure and molecular mechanism of myosins and their cellular roles.