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Record Nr. |
UNINA9910845097703321 |
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Autore |
Finke Peter |
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Titolo |
Modelling Soil Development Under Global Change [[electronic resource] /] / by Peter Finke |
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Pubbl/distr/stampa |
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Cham : , : Springer Nature Switzerland : , : Imprint : Springer, , 2024 |
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ISBN |
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Edizione |
[1st ed. 2024.] |
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Descrizione fisica |
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1 online resource (161 pages) |
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Collana |
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SpringerBriefs in Earth System Sciences, , 2191-5903 |
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Disciplina |
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Soggetti |
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Environment |
Soil science |
Quantum physics |
Computer simulation |
Rock mechanics |
Soil mechanics |
Environmental Sciences |
Soil Science |
Quantum Simulations |
Soil and Rock Mechanics |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Part I. Modelling Soil Development -- 1. Why model soil development -- 2. A brief history of modelling soil development -- 3. Required process coverage in a soil development model -- Part II. The Soilgen Model -- 4. Philosophy behind SoilGen Processes in SoilGen -- 5. Addressing constraints, variability and uncertainty -- Part III. User Interface -- 6. User interface of SoilGen. |
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Sommario/riassunto |
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Quantitative assessments of the effects of global change on soil development are mostly focused on soil carbon, some nutrients, pollutants and soil water. Soil however is a complex entity with interacting biological, physical and chemical processes that are rarely modelled in its entirety. Additionally, for the sake of simplicity various soil properties are considered constants whereas in reality they are not. Soil as we observe it is the resultant of many processes driven by |
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varying boundary conditions such as climate and organisms including men. This is not different when we study global change, thus modelling soil development under global change overlaps with modelling soil formation. This book gives an overview of what such model should entail, with ample descriptions to use SoilGen, a simulattion model to study pedogenesis. |
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2. |
Record Nr. |
UNINA9910380753403321 |
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Titolo |
Cancer Cell Metabolism: A Potential Target for Cancer Therapy / / edited by Dhruv Kumar |
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Pubbl/distr/stampa |
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Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2020 |
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ISBN |
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Edizione |
[1st ed. 2020.] |
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Descrizione fisica |
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1 online resource (XIII, 184 p. 29 illus., 22 illus. in color.) |
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Disciplina |
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Soggetti |
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Cancer |
Medicine - Research |
Biology - Research |
Oncology |
Cancer Biology |
Biomedical Research |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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Chapter 1: Cancer cell metabolism: Solid tumor vs non-solid tumor -- Chapter 2: Reprogramming of cancer cell metabolism: Warburg and Reverse Warburg hypothesis -- Chapter 3: Molecular aspects of cancer cell metabolism: Altered glycolysis and lipid metabolism -- Chapter 4: Understanding the metabolic cross-talk between cancer cells and cancer-associated fibroblasts -- Chapter 5: Metabolic cross-talk between cancer cells and tumor microenvironment -- Chapter 6: Role of autophagy in cancer cell metabolism -- Chapter 7: Role of c-Met/HGF axis in altered cancer metabolism -- Chapter 8: Recent advances in drug development targeting cancer metabolism -- Chapter |
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9: Clinical relevance of “Diagnostic markers” in cancer metabolism -- Chapter 10: Alterations in Metabolite-driven Gene Regulation in Cancer Metabolism -- Chapter 11: Role of Phytochemicals in Cancer Cell Metabolism Regulation. |
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Sommario/riassunto |
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This book illustrates various aspects of cancer cell metabolism, including metabolic regulation in solid tumours vs. non-solid tumours, the molecular pathways involved in its metabolism, and the role of the tumour microenvironment in the regulation of cancer cell metabolism. It summarizes the complexity of cancer cell metabolism in terms of the switch from anaerobic to aerobic glycolysis and how mitochondrial damage promotes aerobic glycolysis in cancer cells. The respective chapters provide the latest information on the metabolic remodelling of cancer cells and elucidate the important role of the signalling pathways in reprogramming of cancer cell metabolism. In addition, the book highlights the role of autophagy in cancer cell metabolism, and how metabolic crosstalk between cancer cells and cancer-associated fibroblasts promotes cancer cell progression. In closing, it summarizes recent advancements in drug development through targeting cancer metabolism. |
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