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1. |
Record Nr. |
UNINA9910220034503321 |
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Autore |
Antonio Porro |
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Titolo |
Grappling with the Multifaceted World of the DNA Damage Response |
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Pubbl/distr/stampa |
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Descrizione fisica |
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1 online resource (306 p.) |
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Collana |
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Frontiers Research Topics |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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DNA damage is a major threat to genomic integrity and cell survival. It can arise both spontaneously and in response to exogenous agents. DNA damage can attack most parts of the DNA structure, ranging from minor and major chemical modifications, to single-strand breaks (SSBs) and gaps, to full double-strand breaks (DSBs). If DNA injuries are mis-repaired or unrepaired, they may ultimately result in mutations or wider-scale genome aberrations that threaten cell homeostasis. Consequently, the cells elicit an elaborate signalling network, known as DNA damage response (DDR), to detect and repair these cytotoxic lesions. This Research Topic was aimed at comprehensive investigations of basic and novel mechanisms that underlie the DNA damage response in eukaryotes.DNA damage is a major threat to genomic integrity and cell survival. It can arise both spontaneously and in response to exogenous agents. DNA damage can attack most parts of the DNA structure, ranging from minor and major chemical modifications, to single-strand breaks (SSBs) and gaps, to full double-strand breaks (DSBs). If DNA injuries are mis-repaired or unrepaired, they may ultimately result in mutations or wider-scale genome aberrations that threaten cell homeostasis. Consequently, the cells elicit an elaborate signalling network, known as DNA damage response (DDR), to detect and repair these cytotoxic lesions. This Research Topic was aimed at comprehensive investigations of basic and novel mechanisms that underlie the DNA damage response in eukaryotes. |
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2. |
Record Nr. |
UNINA9910377825303321 |
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Titolo |
Advances in Water Pollution Monitoring and Control : Select Proceedings from HSFEA 2018 / / edited by Nihal Anwar Siddiqui, S. M. Tauseef, Rajendra Dobhal |
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Pubbl/distr/stampa |
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Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2020 |
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ISBN |
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Edizione |
[1st ed. 2020.] |
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Descrizione fisica |
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1 online resource (XVIII, 179 p. 75 illus., 53 illus. in color.) |
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Collana |
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Springer Transactions in Civil and Environmental Engineering, , 2363-7641 |
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Disciplina |
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Soggetti |
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Civil engineering |
Pollution |
Water |
Hydrology |
Environment |
Civil Engineering |
Environmental Sciences |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Chapter 1: Anchorage System for Penstocks—Case Study of Champawat Town Pumping Water Supply Scheme -- Chapter 2: An Overview on Toxicity, Detection, and Removal of Chromium in Water and WasteWater -- Chapter 3: ‘Phytowaste’ and Vermicomposting as a Potential Route for Its Environmentally Compatible Utilization -- Chapter 4: Microplastic Contamination and Life Cycle Assessment of Bottled Drinking Water -- Chapter 5: Impact of Water Pollution on Endemic Species -- Chapter 6: Physiological Features of Rice Cultivars Which Influence the Quantity of Methane Emitted by the Cultivars. |
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Sommario/riassunto |
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This book presents the proceedings of the International Conference on Health, Safety, Fire, Environment, and Allied Sciences (HSFEA 2018), highlighting the latest developments in the field of science and technology aimed at improving health and safety in the workplace. The volume comprises content from leading scientists, engineers, and policy makers, discussing water pollution and advanced remedial |
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measures, and the impact on health and the environment. Topics of discussion include research on emerging water pollutants, their sources, monitoring and control. The contents of this volume will be of interest to researchers, practitioners, and policy makers alike. |
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