1.

Record Nr.

UNINA9910373918403321

Titolo

Modulation of Oxidative Stress in Heart Disease / / edited by Sajal Chakraborti, Naranjan S. Dhalla, Madhu Dikshit, Nirmal K. Ganguly

Pubbl/distr/stampa

Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019

ISBN

981-13-8946-2

Edizione

[1st ed. 2019.]

Descrizione fisica

1 online resource (XIII, 686 p. 114 illus., 100 illus. in color.)

Disciplina

571.9453

Soggetti

Oxidative stress

Cardiovascular system

Cardiology

Cell physiology

Biochemistry

Biomedical engineering

Oxidative Stress

Cardiovascular Biology

Cell Physiology

Biochemistry, general

Biomedical Engineering/Biotechnology

Estrès (Psicologia)

Malalties del cor

Llibres electrònics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

This book highlights the multifaceted roles of Reactive Oxygen Species (ROS) in modulating normal cellular and molecular mechanisms during the development of different types of heart disease. Each chapter in the book deals with the role that altered redox homeostasis plays in the pathophysiology of heart disease. In addition, the book explains how reactive oxidant species interact with their targets and provides novel strategies for attenuating oxidative stress-induced types of heart



disease. The book not only covers ROS-induced response in heart disease at the cellular level, but also demonstrates that an imbalance of redox states has its roots in our genes, and explains the ways gene expression is regulated. In turn, it reviews potential sources of ROS, their pathological effects on the heart, and potential sites for therapeutic interventions.