1.

Record Nr.

UNINA9910373910303321

Titolo

Genetic Causes of Cardiac Disease / / edited by Jeanette Erdmann, Alessandra Moretti

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019

ISBN

3-030-27371-7

Edizione

[1st ed. 2019.]

Descrizione fisica

1 online resource (407 pages) : illustrations

Collana

Cardiac and Vascular Biology, , 2509-7830 ; ; 7

Disciplina

616.12042

Soggetti

Human physiology

Human genetics

Cardiology

Animal models in research

Human Physiology

Human Genetics

Animal Models

Malalties cardiovasculars

Llibres electrònics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Genetics of adult and fetal forms of Long QT Syndrome -- The genetic landscape of cardiomyopathies. Genetic basis of mitochondrial cardiomyopathy -- The Genetics of Coronary Heart Disease -- Complex genetics and the etiology of human congenital heart disease-Familial Hypercholesterolemia -- Long non-codingRNAs in cardiovascular disease -- Mouse models to study inherited cardiomyopathy -- Interrogating cardiovascular genetics in zebrafish -- Human induced pluripotent stem cells as a platform for functional examination of cardiovascular genetics in a dish -- Systems medicine as a transforming tool for cardiovascular genetics -- Sex differences in prevalent cardiovascular disease in the general population.

Sommario/riassunto

This book provides a comprehensive summary of the latest developments in the field of the genomics of cardiac disease. Written and edited by leading clinicians and scientists involved in the analysis



and therapy of genetic cardiac disorders, it discusses the genetic causes of a variety of cardiac diseases, such as the complex genetics and etiology of congenital heart diseases. It also explores sex differences in prevalent diseases, genetics-based therapeutic strategies and the use of various animal models and alternatives. The book is intended for research scientists and clinical scientists in the cardiovascular field, human geneticists and cardiologists.