1.

Record Nr.

UNINA9910373908403321

Titolo

Behavioral Neurogenomics / / edited by Elisabeth B. Binder, Torsten Klengel

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019

ISBN

3-030-31265-8

Edizione

[1st ed. 2019.]

Descrizione fisica

1 online resource (264 pages)

Collana

Current Topics in Behavioral Neurosciences, , 1866-3370 ; ; 42

Disciplina

616.80442

616.84

Soggetti

Neurosciences

Human genetics

Psychiatry

Neuropsicologia clínica

Genètica de la conducta

Human Genetics

Llibres electrònics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

GWAS of behavioral traits -- Genetic variation in long range enhancers -- DNA methylation and hydroxymethylation and behavior -- Social environment and epigenetics -- Histone modifications and behavior -- Cellular models of neuropsychiatric disorders -- miRNAs and anxiety related behaviors -- Transposable elements -- Inter and transgenerational effects on behavior.

Sommario/riassunto

This book provides a unique overview on the most recent developments in initially diverse areas of behavioral genomic research that now start to intertwine to provide more detailed insights into the complex nature of behavior in health and disease. It focuses on our current understanding of genetic and epigenetic mechanisms of brain function and how they contribute to the complex formation of behavioral traits and psychiatric disorders. Readers experience diverse perspectives of the contributing authors starting from the genetic viewpoint and the effort to establish functional connection between genetic variants and



behavioral phenotypes. Particular attention is given to the broad spectrum of epigenetic mechanisms and behavior. The chapter 'Role of MicoRNAs in Anxiety and Anxiety-Related Disorders', DOI 10.1007/7854_2019_109, available open access under a CC BY 4.0 license at link.springer.com.