1.

Record Nr.

UNINA9910367258103321

Titolo

Hepatitis B Virus Infection : Molecular Virology to Antiviral Drugs / / edited by Hong Tang

Pubbl/distr/stampa

Singapore : , : Springer Singapore : , : Imprint : Springer, , 2020

ISBN

981-13-9151-3

Edizione

[1st ed. 2020.]

Descrizione fisica

1 online resource (VII, 186 p. 19 illus., 14 illus. in color.)

Collana

Advances in Experimental Medicine and Biology, , 0065-2598 ; ; 1179

Disciplina

616.9101

Soggetti

Virology

Infectious diseases

Public health

Infectious Diseases

Public Health

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Preface -- Hepatitis B Virus Infection: Overview -- HBV genome and life cycle -- The regulation of HBV transcription and replication -- Immunopathogenesis of HBV infection -- Cell Culture Models and Animal Models for HBV Study -- Treatment of chronic hepatitis B: current and future.

Sommario/riassunto

This volume provides a state-of-the-art review of the key aspects of HBV. It covers our current understanding of the HBV genome and lifecycle, liver-enriched factors in the regulation of HBV transcription and translation, HBV protein structures and biological functions, and the immunology and pathogenesis of HBV. It also provides an update on cell and animal models, as well as molecular approaches. The respective chapters also cover the clinical management of hepatitis B and discuss future research directions, in particular, the identification of molecular targets for pharmacological intervention. Given its scope, the book offers a valuable resource for students, researchers, clinicians, and health practitioners in the fields of virology, infectious disease, public health etc. Dr Hong Tang is a Professor and Director of the Center of Infectious Diseases, West China Hospital of Sichuan University.