1.

Record Nr.

UNINA9910350349503321

Titolo

Advances in Membrane Proteins : Building, Signaling and Malfunction / / edited by Yu Cao

Pubbl/distr/stampa

Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019

ISBN

981-13-9077-0

Edizione

[1st ed. 2019.]

Descrizione fisica

1 online resource (132 pages)

Disciplina

QP552.M44

Soggetti

Proteins 

Pharmaceutical technology

Protein Science

Pharmaceutical Sciences/Technology

Protein Structure

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

1. Cell adhesion molecules and development -- 2. Receptors and signal transduction -- 3. Single-transmembrane proteins and antibody drugs -- 4. Viral membrane proteins -- 5. Biosynthesis and folding of oily peptide chains -- 6. Quality control in producing membrane proteins.

Sommario/riassunto

This book reviews recent advances regarding the biochemical and biophysical properties of membrane proteins and their applications in biomedicine. Divided into two thematic parts, this second volume addresses proteins’ formation, signaling and malfunctions. It covers a number of important membrane proteins including receptors, cell adhesion molecules, single-transmembrane proteins and viral membrane proteins, and discusses their structures, functions, related diseases, and roles in drug discovery in detail. In turn, the book elucidates the lifecycle of membrane proteins, including their synthesis and facilitated folding process, as well as QC procedures for their production. Additional topics include fundamental concepts, the latest findings, and critical puzzles yet to be solved. Given its scope, the book will appeal to a broad readership in the field of membrane structural and functional biology. Junior scientists can use it as an introduction to the field, while advanced scientists will find a broader view of the field



beyond their area of specialization. .