1.

Record Nr.

UNINA9910350324003321

Autore

Ouyang Liliang

Titolo

Study on Microextrusion-based 3D Bioprinting and Bioink Crosslinking Mechanisms [[electronic resource] /] / by Liliang Ouyang

Pubbl/distr/stampa

Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019

ISBN

981-13-9455-5

Edizione

[1st ed. 2019.]

Descrizione fisica

1 online resource (141 pages)

Collana

Springer Theses, Recognizing Outstanding Ph.D. Research, , 2190-5053

Disciplina

621.988

Soggetti

Biomaterials

Manufactures

Polymers  

Biotechnology

Manufacturing, Machines, Tools, Processes

Polymer Sciences

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Introduction -- General criteria for bioprinting process and bioinks -- Bioprinting of shear-thinning bioink -- Bioprinting of thermo-sensitive bioink -- Bioprinting of non-viscous photo-crosslinkable bioink -- Biological studies and characterization -- Conclusion.

Sommario/riassunto

This book presents a comprehensive study on microextrusion-based 3D bioprinting technologies for bioinks with various crosslinking mechanisms, chiefly focusing on the bioprinting process and bioink properties to provide readers with a better understanding of this state-of-the-art technology. Further, it summarizes a number of general criteria and research routes for microextrusion-based 3D bioprinting using three experimental studies based on shear-thinning, thermo-sensitive and non-viscous hydrogel bioinks. The book also presents sample applications in the areas of stem cells and cell matrix interaction. The book highlights pioneering results in the development of bioprinting technologies and bioinks, which were published in high-quality journals such as Advanced Materials, Biofabrication and ACS Biomaterials Science & Engineering. These include an in-situ



crosslinking strategy that overcomes the viscosity limits for bioinks, which is virtually impossible using conventional strategies, and can be generalized for other bioink formulations.