1.

Record Nr.

UNINA9910350228403321

Titolo

Alcoholic/Non-Alcoholic Digestive Diseases / / edited by Hitoshi Yoshiji, Kosuke Kaji

Pubbl/distr/stampa

Singapore : , : Springer Singapore : , : Imprint : Springer, , 2019

ISBN

981-13-1465-9

Edizione

[1st ed. 2019.]

Descrizione fisica

1 online resource (VIII, 166 p. 25 illus., 19 illus. in color.)

Disciplina

616.33

Soggetti

Gastroenterology

Hepatology

Metabolism - Disorders

Metabolic Diseases

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Part 1 Alcoholic/Nonalcoholic Gastrointestinal Diseases.-1 Alcohol-induced DNA injury in esophagus cancer.-2 Metabolic diseases and GERD -- 3 Post H. pylori gastric diseases.-4 New perspectives in gastric cancer.-5 Role of alcohol and metabolic diseases in colon cancer -- Part 2 Alcoholic/Nonalcoholic Liver Diseases -- 6 Alcoholic liver injury -- 7 Diabetes in liver diseases -- 8 Obesity and hepatocarcinogenesis -- 9 Microbiota in alcoholic liver disease.-10 Microbiota in non-alcoholic liver disease -- 11 Role of oxidative stress in liver disease -- 12 Role of apoptosis in liver disease -- Part 3 Alcoholic/Nonalcoholic Pancreatic Diseases -- 13 Genetic factor in pancreas diseases -- 14 New perspectives in pancreas cancer.

Sommario/riassunto

This book describes the latest advances concerning the molecular mechanisms of and therapeutic strategies for alcohol- and non-alcohol-related digestive diseases. Alcohol abuse causes not only liver injury but can harm various organs, resulting in esophageal and colorectal cancers, GERD, pancreatitis, etc. Similar to alcoholic abuse, metabolic syndrome based on obesity and diabetes is also strongly associated with the development of various digestive diseases. Although these diseases may be differentiated by the presence or absence of alcohol intake, the pathologic findings and pathogenesis



reveal a number of similarities. This volume covers clinical and basic approaches for esophageal, gastric, hepatic, colorectal and pancreatic diseases associated with alcohol abuse and metabolic syndrome; further, it discusses the roles of microbiota, oxidative stress, and apoptosis, the critical factors causing alcoholic and metabolic digestive diseases. Also, it showcases new pathological and therapeutic perspectives in gastric and pancreatic cancers. Alcoholic/Non-Alcoholic Digestive Diseases will provide invaluable information for doctors specializing in gastroenterology and hepatology and researchers seeking new research on digestive diseases based on alcohol consumption and obesity.